CH 3 IMMUNITY Flashcards

1
Q

ACANTHOLYSIS

A

DISSOLUTION OF INTERCELLULAR BRIDGES OF PRICKLE CELL LAYER OF EPITHELIUM

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2
Q

ACQUIRED IMMUNE RESPONSE

A

IMMUNE RESPONSE TO FOREIGN SUBSTANCE BASED ON SPECIFIC MEMORY OF PAST EXPOSURE

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3
Q

ACTIVE IMMUNITY

A

IMMUNITY BASED ON ANTIBODIES DEVELOPED IN RESPONSE TO ANTIGEN, INCLUDES BOTH ACQUIRED & ACQUIRED TYPES

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4
Q

ADJUVANTS

A

AGENTS ADDED TO VAX TO MODIFY IMMUNE RESPONSE

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5
Q

ALLERGEN

A

ANTIGEN THAT PRODUCES HYPERSENSITIVITY OR ALLERGIC REACTION

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6
Q

ALLERGY

A

HYPERSENSITIVITY ACQUIRED THROUGH EXPOSURE TO PARTICULAR ALLERGEN THAT ELICITS AN EXAGGERATED REACTION ON REEXPOSURE TO THE SAME ALLERGEN

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7
Q

ANAPHYLAXIS

A

SEVERE IMMEDIATE TYPE OF HYPERSENSITIVITY, EXAGGERATED IMMUNOLOGIC REACTION OCCURS ON REEXPOSURE TO FOREIGN PROTEIN/SUBSTANCE AFTER SENSITIZATION, RESULTING IN HIVES/ITCHING/SWELLING/VASCULAR COLLAPSE/SHOCK/DEATH

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8
Q

ANTIBODY

A

PROTEIN MOLECULE/IMMUNOGLOBULIN SECRETED BY PLASMA CELLS AND REACTS W/ SPECIFIC ANTIGEN
INCL.) IgA / IgD / IgE / IgG / IgM

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9
Q

ANTIGEN

A

SUBSTANCE ABLE TO INDUCE SPECIFIC IMMUNE RESPONSE

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10
Q

ATTENUATED

A

ABILITY TO REDUCE VIRULENCE OF PATHOGENIC MICROORGANISM BUT STILL KEEP IT VIABLE.
DONE IN DEVELOPMENT OF VAX

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11
Q

AUTOANTIBODY

A

ANTIBODY THAT REACTS AGAINST A TISSUES OF ONE’S OWN BODY

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12
Q

AUTOIMMUNE DISEASE

A

IMMUNOPATHOLOGIC CONDITION CHARACTERIZED BY TISSUE TRAUMA CAUSE BY IMMUNE RESPONSE AGAINST ONE’S OWN BODY

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13
Q

B-CELL LYMPHOCYTE

A

DEVELOPS IN LYMPHOID TISSUE OTHER THAN THYMUS. LATER CAN DIFFERENTIATE INTO PLASMA CELL THAT PRODUCES ANTIBODY.
MAIN INITIATOR OF HUMORAL IMMUNITY.

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14
Q

CELL-MEDIATED IMMUNITY

A

TYPE OF IMMUNITY WHICH MAJOR ROLE IS PLAYED BY T-CELL LYMPHOCYTES

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15
Q

CYTOKINES

A

PROTEINS PRODUCED BY CELLS. INTERCELLULAR COMMUNICATION OR SIGNALING. IMMUNOLOGIC CYTOKINES ARE INVOLVED AS BIOCHEMICAL MEDIATORS IN IMMUNE RESPONSE.

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16
Q

DELAYED HYPERSENSITIVITY

A

TYPE OF HYPERSENSITIVITY REACTION THAT TAKES TIMES TO DEVELOP AFTER T-CELL LYMPHOCYTES PREVIOUSLY INTRODUCED TO ANTIGEN TO EITHER DIRECTLY CAUSE DAMAGE TO TISSUE CELLS OR RECRUIT OTHER CELLS THAT CAUSE DAMAGE

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17
Q

DENDRITIC CELL

A

WBC THAT ACTS AS ANTIGEN-PRESENTING CELL IN SKIN & MUCOSA

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18
Q

DYSGEUSIA

A

ALTERATION IN TASTE

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19
Q

HUMORAL IMMUNITY

A

IMMUNITY IN WHICH BOTH B-CELL LYMPHOCYTES AND ANTIBODIES THEY PRODUCE AS PLASMA CELLS PLAY PREDOMINANT ROLE

20
Q

HYPERSENSITIVITY

A

ALTERED STATE OF REACTIVITY IN WHICH BODY REACTS TO FOREIGN AGENT SUCH AS AN ALLERGEN.
INCLS 4 TYPES OF (TYPE I-IV)

21
Q

HYPOSALIVATION

A

DECREASED SALIVARY FLOW
MAY RESULT IN XEROSTOMA

22
Q

IMMUNE COMPLEX

A

COMBINATION OF ANTIBODY & ANTIGEN PRODUCING COMPLEX THAT CAN INITIATE HYPERSENSITIVITY OR ALLERGIC REACTION

23
Q

IMMUNIZATION

A

INDUCTION OF ACTIVE IMMUNITY. WHEN PATHOGENIC MICROORGANISM USED TO INDUCE ACTIVE IMMUNITY IS ENCOUNTERED THROUGH VACCINATION

24
Q

IMMUNODEFICIENCY

A

TYPE OF IMMUNOPATHOLOGIC CONDITION THAT INVOLVES COMPROMISED OR ENTIRELY ABSENT IMMUNE SYSTEM INVOLVING ITS WBC AND THEIR PRODUCTS

25
Q

IMMUNOGLOBULINS

A

PROTEINS THAT SERVE AS ANTIBODIES DESIGNED TO RESPOND TO SPECIFIC ANTIGEN
SECRETED BY PLASMA CELLS

26
Q

INTERFERON

A

CYTOKINE
FAMILY OF GLYCOPROTEINS THAT HAVE IMMUNOREGULATORY, ANTINEOPLASTIC, AND ANTIVIRAL ACTIVITY

27
Q

LANGERHANS CELL

A

SPECIALIZED DENDRITIC CELL FOUND IN SKIN & MUCOSA INVOLVED IN IMMUNE RESPONSE

28
Q

LE CELL

A

MATURE NEUTROPHIL W/ PHAGOCYTIZED SPHERICAL INCLUSION DERIVED FROM ANOTHER NEUTROPHIL
USED A MARKER OF AUTOIMMUNE DISEASES

29
Q

LYMPHOCYTES

A

WBCs INVOLVED IN IMMUNE RESPONSE THAT HAVE 3 MAJOR SUBSETS: B-CELL LYMPHOCYTE, T-CELL LYMPHOCYTE, NATURAL KILLER CELL

30
Q

LYMPHOID TISSUE

A

COMPOSED OF LYMPHOCYTES SUPPORTED BY MESHWORK OF CONNECTIVE TISSUE
INCL.) TONSILLAR TISSUE, LYMPH NODES, & LYMPHATIC ORGANS

31
Q

LYMPHOKINES

A

SUBSET OF CYTOKINES PRODUCED BY B-CELL OR T-CELL LYMPHOCYTES IN CONTACT W/ ANTIGENS THAT SERVE AS BIOCHEMICAL MEDIATORS IN IMMUNE RESPONSE

32
Q

MACROPHAGE

A

MONONUCLEAR PHAGOCYTE DERIVED FROM MONOCYTES CIRCULATING IN BLOOD, CAN BECOME MOBILE WHEN STIMULATED BY INFLAMMATION AND INTERACT W/ LYMPHOCYTES IN IMMUNE RESPONSE/INFLAMMATION

33
Q

MONOKINES

A

SUBSET OF CYTOKINES
PRIMARILY PRODUCED BY MONOCYTES/MACROPHAGES THAT SERVE AS BIOCHEMICAL MEDIATORS IN IMMUNE RESPONSE

34
Q

MUCOSITIS

A

INFLAMMATION OF MUCOSAL TISSUE DUE TO DISEASE PROCESS

35
Q

NATURAL KILLER CELL

A

TYPE OF LYMPHOCYTE
PART OF INITIAL INNATE IMMUNE RESPONSE
ABLE TO DIRECTLY DESTROY CELLS RECOGNIZED AS FOREIGN

36
Q

NIKOLSKY SIGN

A

DIAGNOSTIC SIGN WHEREBY THE SUPERFICIAL EPITHELIUM SEPARATES EASILY FROM BASAL LAYER ON EXERTION OF FIRM SLIDING MANUAL PRESSURE W/ FINGER OR TONGUE BLADE

37
Q

PASSIVE IMMUNITY

A

IMMUNITY THAT USES ANTIBODIES PRODUCED BY ANOTHER PERSON TO PROTECT INDIVIDUAL AGAINST INFECTIOUS DISEASE
INCL.) NATURAL & ACQUIRED IMMUNITY

38
Q

PLASMA CELL

A

CELL DERIVED FROM B-CELL LYMPHOCYTES THAT PRODUCES ANTIBODIES IN RESPONSE TO PRESENCE OF ANTIGENS

39
Q

RHEUMATOID FACTOR

A

ANTIBODY THAT BINDS TO CERTAIN ANTIBODIES FOUND IN SERUM OF PTS W/ RHEUMATOID ARTHRITIS & CONNECTIVE TISSUE DISEASES (SJOGREN SYNDROME)
CURRENT ASSAYS TEST FOR IgM-CLASS RHEUMATOID FACTOR

40
Q

SCHRIMER TEST

A

MEASURES LACRIMAL GLAND FLOW BY PLACING SPECIAL FILTER PAPER STRIPS INSIDE LOWER EYELID FOR 5MINS

41
Q

SERUM SICKNESS

A

TYPE III HYPERSENSITIVITY
INVOLVES DRUG ALLERGY TO ANTITOXIN SERUM FROM HORSES

42
Q

SYNDROME

A

GROUP OF SIGNS&SYMPTOMS THAT OCCUR TOGETHER

43
Q

SYMBLEPHARON

A

FIBROUS ADHESION B/W EYEBALL & CONJUNCTIVA

44
Q

T-CELL LYMPHOCYTE

A

MATURES IN THYMUS
MAINLY RESPONSIBLE FOR INITIATING CELL-MEDIATED IMMUNITY AND MODULATING HUMORAL IMMUNITY

45
Q

THYMUS

A

CONSISTS OF LYMPHOID TISSUE
LOCATED HIGH IN CHEST
LARGE IN INFANCY, GRADUALLY SHRINKS IN ADULTHOOD
SITE OF T-CELL LYMPHOCYTE MATURATION