Ch. 3 Drugs & Effects Flashcards
Central Nervous System (CNS) consists of..
brain and spinal cord
General Nervous System consists of..
autonomic nervous system and peripheral nervous system
These facilitates message impulses from neuron to neuron as they travel across the synaptic cleft. consists of multiple dendrites
Neurons
These allow the transmission of nerve impulses to the cell body; consist of one axon
Dendrites
These consist of multiple dendrites
Neurons
These consist of one axon
Dendrites
This sends the electrical impulses across the synaptic cleft to the receptor cells of the other neuron *here is where drugs have most devastating effect
Axon
These are naturally occurring chemical substances in the brain; facilitate the electrical impulse form the presynaptic neuron (sender) to postsynaptic neuron (receiver)
Neurotransmitter
Neurotransmitters
send and receive messages in the brain
Major transmitter groups
Catecholamines
Gamma
Peptides
Serotonin
Catecholamines Neurotransmitters
- includes dopamine, norepinephrine, epinephrine
- produced and reabsorbed by the neuron through reuptake
Drugs (cocaine, meth) increase the production and eventual depletion of [transmitter group], thus producing depressive effects following extensive use
Catecholamines Neurotransmitters
Gamma-Aminobutyric Acid and Glutamate (GABA)
Slows and inhibits impulses form nerve to nerve and creates a lethargic/relaxed effect.
Alcohol increases the inhibitory activity of [transmitter group] receptors and decreases the activity of [transmitter group] receptors, thus suppressing brain activity
Gamma-Aminobutyric Acid (GABA) … Glutamate
[transmitter group] regulates sleep, pain, body temperature, and sensory perception
Serotonin
The use of cocaine increases the production of … thus affecting …
serotonin .. sleep, energy and perception
The creation of new neurons throughout the lifetime
Neurogenesis
(How the brain changes) brain plasticity, is an umbrella term that describes lasting change to the brain throughout an animal’s life course. Many aspects of the brain remain changeable (or “plastic”) even into adulthood.
Neuroplasticity
PTSD symptoms/changes in the brain
- decrease in size and level of functioning of hippocampus (primarily responsible for memory)
- increased activity level and blood flow to the amygdala (fear, anxiety, aggression)
- increased levels of cortisol and norepinephrine (stress response)
Factors affecting client’s response to drugs
(1) client’s personal variables (gender, age, race, genetics, expectations, etc.)
(2) enviornmental variables
(3) amount of the drug ingested