Ch 3 Flashcards
Drugs + the Nervous System
neurons
basic building blocks of the nervous system
cells that communicate with one another
dendrites + axon
structures unique to the neuron
axons covered in myelin that conduct electrical signals called __________
action potentials
synapse
junction between 2 neurons
what type of event is a neural transmission
electrochemical
receptor sites
large protein molecules on neurons
2 types of receptors responsible for changes of binding
ionotropic + metabotropic receptors
ionotropic receptors
directly coupled with ion channels
rapid changes, msec in duration
metabotropic receptors
not directly coupled with ion channels
result in delayed changes, long-lasting
T/F : G proteins may initiate synthesis of second messengers
T
mimicry
drugs chemically resembling natural neurotransmitters can bind to receptor sites, fooling them into reacting the same way
affecting enzyme activity
enzyme breakdown + reuptake
agonists
fit receptors and activate them
antagonists
fit but do not activate – stop other things from activating receptors
indirect agonists/antagonists
enhance or inhibit neurotransmitter activity w/o binding to receptors
norepenephrine
discovered early
found outside + inside the brain
what does norepenephrine inside the brain do
regulates hunger, alertness, and arousal
what does norepenephrine outside the brain do
mediates the physical changes of emotional arousal
serotonin
important in regulating sleep
dopamine
regulates coordinated motor movements