Ch 3 Flashcards
Drugs + the Nervous System
neurons
basic building blocks of the nervous system
cells that communicate with one another
dendrites + axon
structures unique to the neuron
axons covered in myelin that conduct electrical signals called __________
action potentials
synapse
junction between 2 neurons
what type of event is a neural transmission
electrochemical
receptor sites
large protein molecules on neurons
2 types of receptors responsible for changes of binding
ionotropic + metabotropic receptors
ionotropic receptors
directly coupled with ion channels
rapid changes, msec in duration
metabotropic receptors
not directly coupled with ion channels
result in delayed changes, long-lasting
T/F : G proteins may initiate synthesis of second messengers
T
mimicry
drugs chemically resembling natural neurotransmitters can bind to receptor sites, fooling them into reacting the same way
affecting enzyme activity
enzyme breakdown + reuptake
agonists
fit receptors and activate them
antagonists
fit but do not activate – stop other things from activating receptors
indirect agonists/antagonists
enhance or inhibit neurotransmitter activity w/o binding to receptors