Ch. 283 Occupational & Environmental Lung Disease Flashcards
A diffuse interstitial fibrosing disease of the lung that is directly related to the intensity and duration of exposure
- Asbestosis
2. Silicosis
Exposure to asbestos has to be at least how long before the disease becomes manifest?
10 years
The chest Xray hallmark of asbestosis
Irregular or linear opacities usually noted 1st at the lower lung fields
HRCT finding distinct in asbestosis
Subpleural curvilinear lines 5-10 mm parallel to pleural surface
Pulmonary function testing in asbestosis reveals a ______ pattern.
Restrictive pattern
This is the most common CA associated with asbestos exposure
Lung cancer
This tumor is associated with asbestos exposure which do not appear to be associated with smoking
Pleural and peritoneal mesotheliomas
Minimum duration of asbestos exposure that has been associated with the development of mesothelioma.
Less than or equal to 1-2 years
Epidemiologic studies show that what percent of mesotheliomas may be associated with asbestos exposure
> 80%
Heavily exposed workers may develop Acute Silicosis with as little as how many months of exposure?
10 months
Characteristic pattern of acute Silicosis in HRCT
Crazy paving
This management of acute Silicosis may provide symptomatic relief and slow the progression
Whole lung lavage
This happens with long term, less intense exposure to silica which appears as small rounded opacities in the upper lobes after 15-20 years of exposure,usually WITHOUT impairment of lung function
Simple Silicosis
In simple silicosis, __________ of hilar nodes may occur and produces a characteristic “eggshell” pattern.
Calcification
This histipathologic finding establishes the diagnosis of BERYLLIUM DISEASE.
Noncaseating granuloma or monocytic infiltration in lung biopsy samples.
