Ch 22 Flashcards
What type of neuronal injury involves swelling of soma and axons “spheroids” (reversible or irreversible)
Reversible
What type of neuronal injury involves displacement of Nissl body and atonal sprouting (reversible or irreversible)
Reversible
What type of neuronal injury involves a soma shrinking, pyknosis, eosinophilia (reversible or irreversible)
Irreversible
What type of neuronal injury involves “red neurons”, cerebral edema, loss of nucleus & Nissl body (reversible or irreversible)
Irreversible
Astrocyte injury leads to ___________ & ___________
Hypertrophy & hyperplasia
Oligodendrocytes are activated after damage to _________ ___________
White matter
Are oligodendrocytes or astrocytes a site for viral inclusions
Oligodendrocytes
What are the phagocytes of the CNS
Microglia
Microglia ________ & __________ after injury
Proliferate and enlarge
___________ cells line ventricles & spinal cord
Ependymal cells
What type of virus invades ependymal cells
Cytomegalovirus
Choroid plexus dysfunction affecting CSF production can be a pathology of what type of cell
Ependymal cell
What type of virus presents with a Negri body
Rabies
What type of virus presents with “owl’s eye appearance”
CMV (cytomegalovirus)
Astrocytes perform __________ (CNS fibrosis)
Gliosis
What neurodegenerative disease produces “Lewy bodies”
Parkinson’s disease
What neurodegenerative disease produces Neurofibrillary tangles and B-amyloid plaques
Alzheimer’s disease
What is lipofuscin
Aging, lipid accumulation
Does vasogenic or cytotoxic edema disrupt the blood brain barrier
Vasogenic edema
Does vasogenic or cytotoxic edema disrupt neuronal/glial membranes
Cytotoxic edema
Is vasogenic or cytotoxic edema intracellular
Cytotoxic edema is intracellular
Does vasogenic or cytotoxic edema lead to extracellular edema
Vasogenic edema leads to extracellular edema
What is the term for increased volume of CSF within ventricles
Hydrocephalus
What is the most common cause of hydrocephalus
Choroid plexus tumor
Is communicating or non communicating hydrocephalus bilateral and even
Communicating hydrocephalus
Is communicating or non communicating hydrocephalus localized and uneven
Noncommunicating hydrocephalus
What percentage of hydrocephalus is idiopathic
50%
Hydrocephalus __ _______ results in infarction or neiurodegeneration
Hydrocephalus ex vacuo
What is the term for increased volume of CSF within ventricles
Hydrocephalus
What is the most common treatment for hydrocephalus
Shunting