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Systems Pathology > Ch 22 > Flashcards

Ch 22 Flashcards

1
Q

What type of neuronal injury involves swelling of soma and axons “spheroids” (reversible or irreversible)

A

Reversible

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2
Q

What type of neuronal injury involves displacement of Nissl body and atonal sprouting (reversible or irreversible)

A

Reversible

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3
Q

What type of neuronal injury involves a soma shrinking, pyknosis, eosinophilia (reversible or irreversible)

A

Irreversible

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4
Q

What type of neuronal injury involves “red neurons”, cerebral edema, loss of nucleus & Nissl body (reversible or irreversible)

A

Irreversible

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5
Q

Astrocyte injury leads to ___________ & ___________

A

Hypertrophy & hyperplasia

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6
Q

Oligodendrocytes are activated after damage to _________ ___________

A

White matter

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7
Q

Are oligodendrocytes or astrocytes a site for viral inclusions

A

Oligodendrocytes

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8
Q

What are the phagocytes of the CNS

A

Microglia

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9
Q

Microglia ________ & __________ after injury

A

Proliferate and enlarge

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10
Q

___________ cells line ventricles & spinal cord

A

Ependymal cells

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11
Q

What type of virus invades ependymal cells

A

Cytomegalovirus

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12
Q

Choroid plexus dysfunction affecting CSF production can be a pathology of what type of cell

A

Ependymal cell

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13
Q

What type of virus presents with a Negri body

A

Rabies

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14
Q

What type of virus presents with “owl’s eye appearance”

A

CMV (cytomegalovirus)

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15
Q

Astrocytes perform __________ (CNS fibrosis)

A

Gliosis

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16
Q

What neurodegenerative disease produces “Lewy bodies”

A

Parkinson’s disease

17
Q

What neurodegenerative disease produces Neurofibrillary tangles and B-amyloid plaques

A

Alzheimer’s disease

18
Q

What is lipofuscin

A

Aging, lipid accumulation

19
Q

Does vasogenic or cytotoxic edema disrupt the blood brain barrier

A

Vasogenic edema

20
Q

Does vasogenic or cytotoxic edema disrupt neuronal/glial membranes

A

Cytotoxic edema

21
Q

Is vasogenic or cytotoxic edema intracellular

A

Cytotoxic edema is intracellular

22
Q

Does vasogenic or cytotoxic edema lead to extracellular edema

A

Vasogenic edema leads to extracellular edema

23
Q

What is the term for increased volume of CSF within ventricles

A

Hydrocephalus

24
Q

What is the most common cause of hydrocephalus

A

Choroid plexus tumor

25
Q

Is communicating or non communicating hydrocephalus bilateral and even

A

Communicating hydrocephalus

26
Q

Is communicating or non communicating hydrocephalus localized and uneven

A

Noncommunicating hydrocephalus

27
Q

What percentage of hydrocephalus is idiopathic

28
Q

Hydrocephalus __ _______ results in infarction or neiurodegeneration

A

Hydrocephalus ex vacuo

29
Q

What is the term for increased volume of CSF within ventricles

A

Hydrocephalus

30
Q

What is the most common treatment for hydrocephalus

Systems Pathology (3 decks)

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