Ch 20, 21 Rxns Flashcards
1
Q
Fisher Esterification
A
NO Phenols/ 3°ROHs
Nucleophilic Substitution @ carbonyl C
2
Q
Esterification via Alkylation (Methyl Ester Synthesis Type I)
A
Methoxy on @ Carbonyl C
Done with COOH Acids
3
Q
Esterification via Alkylation (Methyl Ester Synthesis Type II)
A
**COOH Acid SALT ONLY** (make with K2CO3)
CH3I or benzylic/allylic halides (forces Sn2)
4
Q
Acid Chloride Synthesis
A
Acid + SOCl2 or PCl5
Acid chloride SUPER REACTIVE
5
Q
Dehydration of Carboxylic Acids (Anhydride Synthesis)
A
Use heat or P2O5
6
Q
Anhydride Rehydration (Carboxylic Acid Synthesis Type 5)
A
7
Q
Reduction of Carboxylic Acids
A
8
Q
Decarboxylation (of ß-ketoacids)
A
