Ch 2: Structure and Function of the Nervous System Flashcards
3 main parts of the neuron are
•Dendrites: receiving information, •Soma: assimilating and analyzing information •Axons: conducting the processed information
Glia
provide structural support and insulation for neurons
Oligodendrocytes
myelinate axons in the brain and spinal cord.
Schwann cells
myelinate axons in the periphery of the body.
Electrochemical gradient
gradient of electrochemical potential, usually for an ion that can move across a membrane.
The gradient consists of two parts:
- the chemical gradient, or difference in solute concentration across a membrane
- the electrical gradient, or difference in charge across a membrane.
Ionic concentration gradients (difference in solute concentration across a membrane)
A concentration gradient is the process of particles, called solutes, moving through a solution or gas from an area with a higher number of particles to an area with a lower number of particles. The areas are typically separated by a membrane.
Electrical gradients as force
A electrical gradient refers to the electrical potential that acts on an ion to drive the movement of the ion in one or another direction. and the electrical gradient, or difference in charge across a membrane.
Ion Channels
A single protein or protein complex that traverses the lipid bilayer of cell membrane and form a channel to facilitate the movement of ions through the membrane according to their electrochemical gradient
Ion pumps uses actively transport NA+ ions out of the cell and K+ ions into the cell
Ion pumps work to maintain the concentration gradient. In the case of the sodium-potassium pump, it repeatedly transports 3 sodium ions out of the cell while drawing 2 potassium ions into it.
Concentration gradients move ions to the areas of lowest concentration.
Electrical gradients move ions to areas having the opposite electrical charges.
Universal features of Action Potentials
(1) rising phase (depolarization)
(2) overshoot, and
(3) falling phase (repolarization)
action potentials are seen as brief spikes (+40 mV).
The rising / initial depolarization phase
Neurons will produce an action potential only if the depolarization exceeds threshold of excitation (about 15 mV from resting potential).
Action potentials result in the positively charged sodium ions flow rapidly into the neuron.
Then the charge inside the neuron reverses polarity to become positive, when action potentials are seen as brief spikes (+40 mV).
After depolarization, voltage-gated sodium channels inactivate.
The overshoot phase
The all-or-none law states that a neuron will produce either an action potential of maximal strength or none at all. The determination about whether to send an action potential occurs at the axon hillock.
The Falling / later repolarization phase
The falling phase (3) or the later repolarizing, descending phase of the action potential is mediated by an increase in K+ conductance that occurs when the K+ channels open. During that phase of repolarization by the K+ current, the Na+ channels close.
The absolute refractory phase
The action potential undershoots the resting membrane potential (i.e. hyperpolarized) at the point where the membrane becomes more negative than the resting membrane potential, when the neuron cannot be stimulated no matter how great a stimulus is applied