Ch 2 Health and Safety Flashcards
Dose equals _____ x _____
Concentration x time
Toxicologist list 4 categories of factors that influence toxicity
Concentration or dose
Rate of absorption
Rate of detoxification
Rate of excretion
Two units of measurement commonly sided for determining the relative toxicity of a chemical substance or compound
Lethal dose, 50% kill
Lethal concentration 50% kill
The concentration and ingested, absorbed or injected substance, which result in the death of 50% of the test population. This is an oral or dermal exposure expressed in terms of weight – MG/KG.
Lethal dose, 50% kill (LD50)
The concentration of an inhaled substance that results in the death of 50% of the test population in a specific time.
Lethal concentration, 50% kill (LC50)
Maxim, everyone concentration of a material of which an average healthy person may be exposed repeatedly for eight hours each day 40 hours per week without suffering adverse effects ACGIH
TLV/TWA
Maximum time weighted concentration at which 95% of expose healthy adults suffer no adverse effects over a 40 hour work week (2 different)
Permissible exposure limit - OSHA - 8 hour concentration
Recommended exposure levels - Niosh - 10 hour concentration
15 minute time weighted average exposure not repeated more than four times daily with a 60 minute rest.
Short term exposure limit
The maximum concentration that should not be exceeded even instantaneously
TLV/C threshold limit value ceiling
(ACGIH recommends 5 times TLV/TWA used in place of TLV/C)
Three general IDLH atmospheres
Toxic
Flammable
Oxygen deficient
Consider 10 times TLV/TWA as IDLH
This is defined as the maximum air concentration below, which it is believed that nearly all individuals could be exposed for up to 1 hour, without experiencing or developing reversible, or other serious health effects or symptoms
ERPG – 2
How many tiers are there within the Emergency Response Planning Guidelines ERPG? (AIHA)
3
How many tiers and periods are within the Acute Emergency Exposure Guidelines AEGL? (EPA)
3 tiers
5 periods
10 min, 30 min, 1 hr, 4 hr, 8 hr
Four types of ionizing radiation
Alpha, beta, gamma neutron
Characterized by its lack of energy to remove electrons from atoms
Non-ionizing radiation
Characterized by its ability to create charge particles or ions in anything it strikes. X-rays are a familiar form of this
Ionizing radiation
There are blank types of ionizing radiation. How many and what are they?
Four: Alpha Beta, gamma neutron
Largest of the common radioactive particles travel only 3 to 4 inches in air, stop by sheet of paper, primarily an internal hazard greatest health hazard when they enter the body
Alpha
A particle that is the same size as an electron can travel several yards in air, penetrate paper and human skin, cannot penetrate internal organs, internal and external radiation hazard
Beta
Most dangerous form of common radiation, because of the speed at which it moves penetrates most materials very well, considering a whole body hazard
Gamma
Emitted high-speed from the nucleus of a radioactive atom
considered a whole body hazard
Neutron particles