Ch. 2 Flashcards

1
Q

Bioavailability

A

% of drug dosage absorbed

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2
Q

Drug Dependence

A

reliance on a drug, characterized by physical &/or psychological dependence

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3
Q

Drug Addiction

A

drug abuse & dependence characterized by compulsive behavior

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4
Q

Drug Absorption

A

from site of administration into bloodstream

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5
Q

Drug Distribution

A

from bloodstream into tissues and organs

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6
Q

Drug Metabolism

A

aka biotransformation; chemical alteration of drugs in the body

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7
Q

DMMS

A

drug microsomal metabolizing system; enzymes in the liver responsible for drug metabolism

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8
Q

Enzyme Induction

A

stimulation of DMMS via administration of certain drugs

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9
Q

Enzyme Inhibition

A

inhibition of DMMS via administration of certain drugs

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10
Q

First-Pass Metabolism

A

when drugs undergo significant metabolism in the liver during first pass through

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