Ch. 2 Flashcards
Bioavailability
% of drug dosage absorbed
Drug Dependence
reliance on a drug, characterized by physical &/or psychological dependence
Drug Addiction
drug abuse & dependence characterized by compulsive behavior
Drug Absorption
from site of administration into bloodstream
Drug Distribution
from bloodstream into tissues and organs
Drug Metabolism
aka biotransformation; chemical alteration of drugs in the body
DMMS
drug microsomal metabolizing system; enzymes in the liver responsible for drug metabolism
Enzyme Induction
stimulation of DMMS via administration of certain drugs
Enzyme Inhibition
inhibition of DMMS via administration of certain drugs
First-Pass Metabolism
when drugs undergo significant metabolism in the liver during first pass through