Ch 17 Quantitative Genetics Flashcards

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1
Q

quantitative genetics

A

genetic analysis of complex characteristics such as the oil content of corn

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2
Q

continuous characteristics

A

characteristics vary continuously along a scale of measurement
also called quantitative characteristics because any individuals phenotype must be described by a quantitative measurement

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3
Q

two phenomena for quantitative characteristics

A

1) many are polygenic: influenced by genes at many loci
2) often arise when environmental factors affect the phenotype because environmental differences result in a single genotype producing a range of phenotypes

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4
Q

multifactorial

A

most continuously varying characteristics are both polygenic and influenced by environmental factors

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5
Q

threshold characteristic

A

a type of quantitative characteristic that is present or absent
they exhibit only two phenotypes; are determined by multiple genetic and environmental factors

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6
Q

frequency distributions

A

a graph of the frequencies (numbers or proportions) of the different phenotypes

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7
Q

normal distribution

A

many quantitative characteristics exhibit a symmetrical (bell-shaped) curve
arise when a large number of independent factors contribute to a measurement

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8
Q

types of distribution

A

normal, skewed and bimodal

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9
Q

mean

A

also called the average, is a statistic that provides information about the center of a distribution

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10
Q

variance

A

indicates the variability of a group of measurements, or how spread out the distribution is
the larger the variance, the greater the spread of measurements in a distribution around its mean

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11
Q

heritability

A

proportion of the total phenotypic variation that is due to genetic differences
if increased, then largely genetic
if decreased, then largely enviromental

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12
Q

phenotypic variation

A

represented Vp
we could collect a representative sample of plants from the population, weigh each plant in the sample, and calculate the mean and variance of plant weight

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13
Q

genetic variance

A

represented Vg

differences in genotypes among individual members of the population

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14
Q

environmental variance

A

represented Ve
differences in phenotype may be due to environmental differences among the plants
includes differences in environmental factors such as the amount of light or water that the plant receives; it also includes random differences in development that cannot be attributed to any specific factor

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15
Q

genetic-environmental interaction variance

A

represented Vge

arises when the effect of a gene depends on the specific environment in which it is found

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16
Q

additive genetic variance

A

represented Va
comprises the additive effects of genes on the phenotype, which can be summed to determine the overall effect on the phenotype
primarily determines the resemblance between parents and offspring

17
Q

dominance genetic variance

A

represented Vd
the effects of some genes have a dominance component
the effect of an allele depends on the identity of the other allele at that locus

18
Q

gene interaction variance

A

represented Vi

genes at different loci may interact in the same way that alleles at the same locus interact

19
Q

broad-sense heritability

A

represented H^2
represents the proportion of phenotypic variance that is due to genetic variance
H^2 = 1 then all your phenotypic variance is due to genetic variance
H^2 = 0 then little phenotypic variance, it is due to environment

20
Q

narrow-sense heritability

A

represented h^2

equal to the additive genetic variance divided by the phenotypic variance

21
Q

limitations of heritability

A
  1. Does not indicate the degree to which a characteristic is genetically determined
  2. an individual does not have heritability
  3. no universal heritability for a characteristic
  4. even when heritability is high, environmental factors can influence a characteristic
  5. heritabilities indicate nothing about the nature of population differences in a characteristic
22
Q

quantitative trait loci (QTLs)

A

chromosome regions with genes that control polygenic characteristics
a map location for a chromosome region that is associated with a quantitative trait

23
Q

natural selection

A

arises through the differential reproduction of individuals with different genotypes

24
Q

artificial selection

A

humans have practiced a form of selection by promoting the reproduction of organisms with traits perceived as desirable

25
Q

response to selection

A

the extent to which a characteristic subjected to selection changes in one generation
represented by R and is the difference between the original population and offspring
R= offspring - original population

26
Q

selection differential

A

the response to selection thus depends on the degree to which the selected parents differ from the rest of the population
defined as the difference between the mean phenotype of the selected parents and the mean phenotype of the original population
S= breeding parents - original population

27
Q

realized heritability

A

heritability determined by a response-to-selection experiment
if certain assumptions are met, this is identical to narrow-sense heritability

28
Q

standard deviation

A

expressing deviation from mean in same scale of measurement mean