CH 16 Flashcards

Schizophrenia

You may prefer our related Brainscape-certified flashcards:
1
Q

Positive Symptoms

A

Delusions
Hallucinations
Disorganized thinking, speech, and behavior (psychosis)
- associative looseness
- bizarre behavior
- echolalia
- echopraxia
- flight of ideas

Ambivalence
Ideas of Reference
Perseveration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Negative Symptoms

A

Flat affect
Anhedonia
Lack of volition (Avolition)
Social withdrawal or discomfort (Asociality)

Alogia
Apathy
Blunted affect
Catatonia (involves echolalia, echopraxia)
Inattention

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Schizoaffective Disorder (SCA/SAD), diagnosis:

A

Psychosis +
Mood disorder (depression or bipolar disorder)

Uninterrupted illness:
Positive or negative symptoms (positive symptoms for at least 2 weeks) +
Mood disorders (major depressive, manic, or mixed)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Schizoaffective Disorder (SCA/SAD), treatment:

A

1st choice: atypical AP
+ mood stabilizers or antidepressants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

True or False: The earlier onset, the worse the outcome/ progression of Schizophrenia?

A

True

greater cognitive impairment
poorer premorbid adjustment
more prominent negative signs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Higher relapse rates due to:

A

non-adherence to medication
negative attitude toward treatment
caregiver criticism
persistent substance use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Improved outcomes for Schizophrenia (3):

A

lower relapse rate
improved QOL, insight, social functioning

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Schizophreniform disorder

A

Acute, reactive psychosis for less than 6 months

If more than 6 months, upgraded to dx of Schizophrenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Delusions

A

fixed, false beliefs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Hallucinations

A

false sensory perceptions (auditory, visual, tactile, olfactory, gustatory)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Schizophrenia, etiology:

A

biological predisposition/ vulnerability (genetics, neuroanatomy, neurochemical, immunovirologic)

environmental stressor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Schizophrenia, neurochemical irregularities:

A

Excess dopamine
Low serotonin (modulates excess dopamine) or excess serotonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Neuroleptics

A

Antipsychotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Conventional/ Typical Antipsychotics, class and MOA:

A

Dopamine antagonists

Decrease positive symptoms (temporal lobe)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Atypical Antipsychotics, class and MOA

A

Diminish positive symptoms

Lessen negative symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

LAIs (Long-Acting Injections) APs (6)

A

not for acute episodes, may need oral stabilizing before transition to depot

Fluphenazine (Prolixin): 7 - 28 days
Haloperidol (Haldol): 4 weeks
Risperidone (Risperdal)
Paliperidone (Invega)
Olanzapine (Zyprexa)
Aripiprazole (Abilify)

17
Q

Serious neurologic SEs of APs (4)

A

EPS (acute dystonic reactions, akathisia, pseudoparkinsonism)

Tardive dyskinesia (TD)

Seizures

Neuroleptic malignant syndrome (NMS)

18
Q

Non-neurologic SEs of APs

A

weight gain
sedation
photosensitivity
anticholinergic sx (dry mouth, blurred vision, constipation, urinary retention, orthostatic hypotension)

19
Q

Acute dystonic reactions (EPS) -

A