Ch 10 - HPV-Mediated (p16+) Oropharyngeal Cancer

Question 1

T0

Answer 1

No primary identified. (Must have had p16 testing to classify as T0 in this system.)

Question 2

T1

Answer 2

Tumor 2cm or smaller in greatest dimension

Question 3

T2

Answer 3

Tumor larger than 2cm but not larger than 4cm in greatest dimension

Question 4

T3

Answer 4

Tumor larger than 4cm in greatest dimension or extension to lingual surface of epiglottis

Question 5

T4

Answer 5

Moderately advanced local disease. Tumor invades the larynx, extrinsic muscle of tongue, medial pterygoid, hard palate, or mandible, or beyond*

*Mucosal extension to lingual surface of epiglottis from primary tumors of the base of the tongue and vallecula does not constitute invasion of the larynx

Question 6

Nx

Answer 6

Regional lymph nodes cannot be assessed

Question 7

N0

Answer 7

No regional lymph node metastasis

Question 8

N1

Answer 8

One or more ipsilateral lymph nodes, none larger than 6cm

Question 9

N2

Answer 9

Contralateral or bilateral lymph nodes, none larger than 6cm

Question 10

N3

Answer 10

Lymph node(s) larger than 6cm

Question 11

pN0

Answer 11

No regional lymph node metastasis

Question 12

pN1

Answer 12

Metastasis in 4 or fewer lymph nodes

Question 13

pN2

Answer 13

Metastasis in more than 4 lymph nodes

Question 14

What is the staging for:

T0/1/2, N0/1, M0?

Answer 14

Stage I

Question 15

What is the stage for:

T0/1/2, N2, M0?

Answer 15

Stage II

Question 16

What is the stage for:

T3/4, N0/1, M0?

Answer 16

Stage II

Question 17

What is the stage for:

T3/4, N2, M0?

Answer 17

Stage III

Question 18

What is the stage for:

Any T, Any N, M1?

Answer 18

Stage IV