Ch. 10

Question 1

What does pyruvate dehydrogenase catalyze in the PDH complex? What are its coenzymes?

Question 2

What does dihydrolipoyl transacetylase catalyze in the PDH complex? What are its coenzymes?

Question 3

What does dihydrolipoyl dehydrogenase catalyze in the PDH complex? What are its coenzymes?

Question 4

Which enzyme in the PDH complex removes CO2?

Answer 4

Pyruvate dehydrogenase component

Question 5

Which enzyme in the PDH complex moves acetyl group from one enzyme to a coenzyme?

Question 6

Which enzyme in the PDH complex oxidizes enzyme 2 to ultimately reduce which coenzyme?

Question 7

Where do the main products in the PDH complex go next? (acetyl co A compared to NADH vs FADH2)

Question 8

How is the PDH complex regulated allosterically?

Question 9

What are the steps of the citric acid cycle?

Question 10

Where does the citric acid cycle take place?

Question 11

How is the citric acid cycle regulated allosterically?

Question 12

How do you predict positive/negative regulators in glycolysis?

Question 13

How do you predict positive/negative regulators in the citric acid cycle?

Question 14

How do you predict positive/negative regulators in the PDH complex?

Question 15

How do the products (CO2 and protons) of the reduction of NAD+ play a role in oxygen delivery with hemoglobin?

Question 16

Which enzymes are oxido-reductases?

Question 17

Which coenzymes are reduced? How many?

Question 18

What is the high energy intermediate in the citric acid cycle?

Question 19

What is the role of role of acetyl co A vs. succinyl coA in the citric acid cycle?

Question 20

How is the alpha ketoglutarate dehydrogenase complex similar to and different from the PDH complex?