CH. 1 Flashcards
Axial Skeleton
Skull, vertebral column, ribs and sternum
Appendicular Skeleton
Shoulder, pelvic girdle & bones in extremities
Fibrous joints
Allow virtually no movement (structures of the skull)
Cartilaginous joints
Allow limited movement (intervertebral disks)
Synovial joints
Allow considerable movement (knee, elbow)
Bone Periosteum
Specialized connective tissue that covers all bones that tendons attach to
Epimysium
Outer connective tissue surrounding the muscle
Perimysium
Middle connective tissue surrounding fasciculi (a bundle of muscle fibers)
Endomysium
Inner connective tissue surrounding each individual muscle muscle fiber and is contiguous with the muscle fiber’s membrane: Sarcolemma
Muscle fiber content
Sarcolemma (membrane)
Protein myofibrils
Additional protein
Stored glycogen
Fat particles
Enzymes
Mitochondria
Sarcoplasmic reticulum
Sarcomere
Smallest contractile unit in a muscle
Myofibrils
Composed of actin and myosin myofilaments that are organized longitudinally in the sarcomere
T tubules
Run perpendicular to the sarcoplasmic reticulum and terminate near the Z line between two sarcomeres. Contiguous with the Sarcolemma and deliver the signal from the motor neuron simultaneously to all depths of the muscle fiber
Sarcoplasmic Reticulum
Intricate system of tubules that surround each myofibril and contains calcium ions that regulate muscle contraction
A band
Alignment of myosin filaments
I Band
Contains actin filaments
Z line
Splits the I band and separates sarcomeres
H zone
Center of sarcomeres that contain myosin filaments
Motor unit (components)
Motor neuron
NM Junction
Corresponding muscle fibers
Motor neurons
Nerve cells responsible for innervating muscle fibers. 1 motor neuron can innervate up to thousands of muscle fibers
All or nothing principal
All muscles within a motor unit contract simultaneously when a motor unit delivers the signal to contract by the discharge of action potential. A stronger action potential CAN’T
produce a stronger muscle contraction
Action potential
Release of acetylcholine at nerve terminal. Diffuses across NM junction and excites the Sarcoplasmic reticulum/Sarcolemma and the fibers contract to merge and completely fuse
What are the 5 phases of the Sliding Filament Theory?
Resting phase
Excitation-Contraction Coupling phase
Contraction phase
Recharge phase
Relaxation Phase
Resting Phase
- Majority of calcium is stored in Sarcoplasmic reticulum
- Few myosin crossbridges are bound to actin
Vertebral Column
7 cervical vertebrae
12 thoracic vertebrae
5 lumbar vertebrae
5 sacral vertebrae
3-5 coccygeal
Excitation-Contraction Coupling Phase
-Nervous System signals the motor unit to contract
-Action Potential discharges across NM junction
-Calcium is released from Sarcoplasmic reticulum
-Calcium ions bind with troponin on actin
-H zone and I-Band shrink
-Z lines pull together as sarcomere shrinks
Contraction Phase
- ATP on the myosin crossbridge breaks down via hydrolysis, catalyzed by enzyme ATPase
- Breakdown of ATP to ADP and phosphate delivers the energy for the pulling action aka power stroke
Recharge Phase
- New ATP replaces ADP on the myosin crossbridge
- If calcium, ATP & ATPase are available, contraction repeats
Relaxation Phase
- Calcium pumped back into Sarcoplasmic Reticulum
- Actin and myosin return to unbound state
- Muscle Relaxes
Type I Fibers (slow twitch)
-Efficient
-Resistant to fatigue
-High capillary density/density of mitochondria
-High capacity for aerobic energy
-Low recruitment threshold (activated at lower demand unlike Type II)
-Limited potential for rapid Force development & anaerobic power