Ch 1 Flashcards

1
Q

Limbic region includes

A
Hippocampus 
Amygdala 
Hypothalamus 
Parahippocampal gyrus
Cingulate cortex
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2
Q

Hippocampus role

A

Memory

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3
Q

Amygdala role

A

Important element of fear circuitry and assigning emotional valence to stimuli

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4
Q

Frontal lobe involved in

A
Planning 
Attention
Abstract thought 
Problem solving 
Judgement 
Inhibition of impulses
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5
Q

Involved in emotion and memory

A

Limbic system

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6
Q

part of brain known for its role in motor coordination and learning. Also fir cognitive &affective processes

A

Cerebellum

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7
Q

Major relay station for sensory information

A

Thalamus

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8
Q

Part of the brain that plays a critical role in Neuroendocrine regulation

A

Hypothalamus

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9
Q

Mood, motivation, sexual drive, hunger, temperature, and sleep (brain region)

A

Hypothalamus

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10
Q

Two classes of cells in the brain

A

Neurons and glia

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11
Q

Neurotransmitter characteristics

A

Synthesized within the presynaptic neuron

Released with depolarization from the presynaptic neuron to exert a discrete action on the postsynaptic neuron

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12
Q

They are action on the postsynaptic neuron can be replicated by administering a drug

A

Neurotransmitter

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13
Q

What are neurotransmitters made up of

A

Amino acids, biogenic amines, nitrous oxide, larger peptides (opioids &substance P)

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14
Q

Amino acids

A

Glutamate

GABA

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15
Q

Monoamines

A
Dopamine 
Norepinephrine 
Epinephrine 
Serotonin 
Histamine
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16
Q

Small molecule neurotransmitter

A

Acetylcholine

17
Q

Peptide neurotransmitters

A
Opioids
Hypothalamic factors (CRH,orexins)
Pituitary hormones ((ACTH, TSH, oxytocin,vasopressin)
CNS peptides (sub p, etc)
Leptin
18
Q

Rapid a fact Nero transmitter receptor

A

NMDA

19
Q

Not essential amino acid neurotransmitter that does not cross the blood brain barrier

A

Glutamate

20
Q

Synthesis of glutamate neurotransmitter relies entirely on conversion from its precursors___&___

A

Glutamine and aspartate

21
Q

What do NMDA receptor’s and anti-receptors mediate?

A

They mediate long-term potential in the hippocampus, a process critical for hippocampal dependent memory formation

22
Q

Large calcium and flex resulting in cell death

A

Excitotoxicity

23
Q

Synthesized from glucose, converted via Krebs cycle into a-ketoglutarate then glutamate 

A

GABA

24
Q

Neurotransmitter functioning in CNS and peripherally. Also a neuromodulator potentiated in the excitability of other neurotransmitter systems

A

Histamine

25
Q

Nero transmitter important role in central and peripheral neurophysiology.

A

ACH

26
Q

Precursor of ACh

A

Choline

27
Q

Anti-cholinergics medication‘s affect the balance of &. Can improve EPS in pts with movement disorders

A

Dopamine and ACh

28
Q

Histamine stimulates

A

Wakefulness, suppresses appetite, may enhance cognition through its excitatory effects on brain stem and hypothalamic neurons

29
Q

What brain territory is most likely considered as the major relay station for incoming sensory information

A

Thalamus

30
Q

Dry mouth, constipation, urinary hesitancy, poor concentration side effects from binding to what receptors?

A

Muscarinic cholinergic receptors