CF Flashcards
0
Q
Median age of CF survival
A
~41 yrs old
1
Q
Describe pulmonary and extrapulmonary manifestations of CF
A
Multi organ dz
2
Q
CFTR
A
Chloride channel that helps maintain airway surface liquid necessary for lung clearance
3
Q
Mutations
A
.
4
Q
Common features of CF
A
CF PANCREAS C hronic cough F ailure to thrive P ancreatic insufficiency A lkalosis N eonatal intestinal obstruction / nasal polyps C lubbing R ectal prolapse E lectrolyte abnormalities A bsence of vas deferens S putum / sinus disease
5
Q
Common CF pathogens
A
Pseudo aeruginosa
Burkholderia cepacia
MRSA
Aspergillus
6
Q
When do we treat CF with positive cultures?
A
When pt exhibits signs of pulmonary exacerbation
7
Q
Symptoms of pulmonary exacerbation
A
Increase cough frequency Increase SOB Increase sputum production Decreased exercise tolerance Decreased appetite Congested
8
Q
Signs of pulmonary exacerbation
A
Increase respiratory rate Use of accessory muscles for breathing Decline in PFTs Fever and leukocytosis Weight loss New infiltrate on chest radiograph
