Cervical CA Flashcards

1
Q

most cervical CA is of what cell type?

A

squamous cell

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2
Q

most squamous cell cervical CA is related to what virus?

A

HPV

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3
Q

20% of cervical CA are of what cell type?

A

adenocarcinoma

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4
Q

adenocarcinoma of the cervix is mainly of what etiology?

A

maternal DES exposure (diethylstilbestrol)

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5
Q

how is cervical CA staged?

A

clinically

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6
Q

mucus-filled cyst on the surface of the cervix

A

nabothian cysts (as per Couli, most common lesion on the cervix)

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7
Q

mets of cervical CA is most likely where?

A

RIB Eye (rectal, intra peritoneal, bladder, endometrial) .. remember the hematogenous spread is BLBL (breast, lung, bone, liver)

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8
Q

what is removed during a radical hysterectomy?

A

uterus, cervix, parametrial tissue and upper vagina

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9
Q

what is the treatment for invasive cervical CA?

A

radical hysterectomy w/lymph node dissection

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10
Q

for which stage of cervical CA is a radical hysterectomy recommended?

A

low stages

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11
Q

in terms of follow-up care of cervical carcinoma, what is the protocol? (be specific!)

A

PE every three months for the first 2 yrs then every 6 months for year 3-5 and then annually; PE includes: pap, chest x-ray, and ct scan of abdomen

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12
Q

t or f: approximately 30% of pts treated for cervical CA will have recurrence

A

TRUE - typically it returns in the pelvis

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13
Q

in addition to vaginal bleeding, pelvic and leg pain - what is one other sign that should trigger you to think recurrence of cervical CA?

A

sacral backpain/ache in sciatic distribution

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14
Q

what is the major cause of death in cervical CA?

A

uremia due to periuretal compression of the tumor

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15
Q

t or f: 1/3 of pregnant patients with cervical CA are asymptomatic

A

TRUE

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16
Q

what is the basic treatment for invasive cervical CA if confined to the cervix?

A

radical hysterectomy w/ pelvic lymphadenectomy; if beyond the cervix, chemo and radiation

17
Q

t or f: therapeutic conization is contraindicated in pregnancy

A

TRUE

18
Q

t or f: ECC is contraindicated in pregnancy

A

TRUE

19
Q

t or f: chemotherapy is contraindicated in pregnancy, but radiation is OK

A

FALSE; radiation is contraindicated, but chemotherapy is acceptable for treatment of cervical CA`

20
Q

in terms of cervical CA and delivery, @ what stage are patients candidates for vaginal delivery?

A

early small volume stages - when @ greater stages, pt must get c section

21
Q

what is the average age of a pt with adenocarcinoma of the cervix?

A

16-27 years old

22
Q

what is the treatment of adenocarcinoma of the cervix?

A

radical hysterectomy and pelvic lymph node dissection

23
Q

t or f: most DES-related CA recur within three years of initial treatment?

A

TRUE