Cerebral vasc and Brain Ibook

Question 1

What ions will affect our cell the most if extracellular conX change?

Answer 1

K- bc K leak channels operate at rest. hyperK = depolarize cell

Cl- can enter cell at rest (small)

Question 2

For the parasympathetic system, post ganglionic cells release what NT for what receptor?

Answer 2

NT= Ach
Rec = muscarinic (1 of 3 types)

Question 3

types of muscarinic:
M1=
M2=
M3=

Answer 3

M1= salivation, smooth m.
M2= heart pacemaker, slows heart
M3=sweating/exocrine gland

Question 4

For symp system post ganglionic use what NT for what receptor?

Answer 4

NT= norepi
Rec= adrenergic (2 types)

Question 5

Alpha vs beta adrenergic receptors

Answer 5

a= smooth m contraction
b= relax, 1= inc HR/contractility

Question 6

Blood pressure eq

Answer 6

SVxHRxTPR

Question 7

What regulates systemic arterial blood flow

Answer 7

carotid and aortic baroreceptors. stretch receptors. at high BP firing rate high

Question 8

The afferents from baroreceptors synapse where

Answer 8

set of neurons in the nucleus tractus solitarius, those axons then go to vasomotor centers in brain stem

Question 9

Within vasomotor centers in brainstem you find what regions

Answer 9

depressor regions: PS, lower BP

Pressor region: sym, raise BP
systemically

Question 10

Locally blood flow is regulated by what?

Answer 10

local metabolic agents. (adenosine, K, lactic acid) these cause vasodilation

Question 11

Systemic vs local blood flow

Answer 11

the central mechanisms mediated by baroreceptors will override local.

Question 12

what 3 areas never receive reduced blood flow

Answer 12

heart, lungs and brain