Cerebellar Dysfunction Flashcards

1
Q

what are the functions of the cerebellum?

A

called the “little brain
4 main functions
1. maintenance of balance and posture
2. coordination of voluntary movements ➔ fine movements
3. motor learning ➔ riding a bike or learning a sport
4. cognitive function ➔ language

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2
Q

what general physical manifestations may occur with cerebellar dysfunction?

A

balance problems and gait disorders + difficulties in coordination

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3
Q

what does DANISH stand for for cerebellar dysfunction?

A

D - dysdiadochokinesia
A - ataxia
N - nystagmus
I - Intention tremor
S - scanning speech
H - hypotonia

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4
Q

what does dysdiadochokinesia stand for? what p/e can you do to test for it?

A

inability to perform rapid alternating movements

upper: finger tapping (thumb + pointer finger) or pronation/supination
lower: toe tapping

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5
Q

what does ataxia stand for? what p/e can you do?

A

loss of muscle control in arms and legs

gait - tandem walking, broad-based, Romberg’s stance

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5
Q

what does Romberg’s stance tell you?

A

if positive ➔ imbalanced with eyes closed and feet together = cerebellar problem

swaying or falling

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6
Q

what does nystagmus stand for? what test can you do to test?

A

repetitive uncontrolled eye movements
H-test
- horizontal is less concerning; vertical is concerning

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7
Q

what does intention tremor mean? how to test?

A

tremor that appears with goal-directed movement at the end of the movement

finger-to-nose test ➔ overshooting or undershooting of the pt’s index finger d/t improper movement coordination

heel-to-shin test

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8
Q

what does scanning speech look like?

A

pauses after each word, as if they are searching for words

also known as dysarthria: scanning or slurred speech

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9
Q

what does hypotonia look like? what test to examine?

A

decrease tone ➔ decrease resistance to passive muscular extension

normal p/e assessing for tone ➔ passive ROM

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10
Q

what other symptoms could a pt experience with cerebellar dysfunction beyond DANISH?

A
  • dysmetria: irregular placement during voluntary movement of limb or eye ➔ finger to nose/heel to chin test
  • postural instability
  • pendular patellar reflex
  • rebound phenomenon: over-correction after limb displacement
  • hypermetric saccades ➔ cannot track objects with smooth eye movements
  • pronator drift
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11
Q

common causes for cerebellar dysfunction

A
  1. head trauma
  2. toxins and drugs ➔ ALCOHOL
  3. vitamin deficiency ➔ B, E, THIAMINE (relate to alcohol)!!
  4. infectious ➔ HIV, neurosyphilis, brain abscess, HIV
  5. hereditary: ataxia telangiectasia etc.
  6. autoimmune: MS or GBS
  7. Vascular: stroke
  8. space-occupying lesions: tumours, neurofibromatosis
  9. paraneoplastic syndromes
  10. neurodegenerative diseases – parkinson disease or Huntington disease
  11. metabolic conditions: thyroid, Hashimoto, Wilson, Celiac
  12. Psychiatric: schizophrenia
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12
Q

what is Wenicke-Korsakoff Syndrome?

A

its a group of alcohol induced amnestic disorders d/t thiamine deficiency (poor nutrition or malabsorption)

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13
Q

def Wenicke’s encephalopathy + s/s

A

acute and reversible
triad of oculomotor dysfunction (nystagmus; CN VI palsy), gait ataxia, and confusion

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14
Q

def Korsakoff’s syndrome + s/s

A

chronic and only ~20% reversible

s/s: anterograde amnesia (no ST memories), and confabulation ➔ persists beyond usual duration of intoxication and withdrawal

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15
Q

how do you tx wernicke’s encephalopathy?

A

THIAMINE ➔ can also give to any pt in alcohol withdrawal (for preventative or acute management)
folic acid supplementation

16
Q

how do you tx Korsakoff’s syndrome?

A

thiamine! folic acid supplementation

17
Q

how can we provide support for alcohol cerebellar degeneration?

A

harm reduction approach: social support, EtOH cessation, local community health centre resources
nutrition: thiamine and folic acids

PT, OT, assistive devices, fall prevention, gait training

18
Q

Cx from alcohol use

A
  • cirrhosis
  • Wernicke Korsakoff syndrome
  • HTN
  • Gout
  • alcoholic ketoacidosis
  • fetal alcohol syndrome
  • holiday heart - alcohol-induced myopathy
  • pancreatitis
  • hepatic encephalopathy - astreixis
  • gastritis and malabsorption
  • neuropathy