Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology Elon > Cephlaspoins > Flashcards

Cephlaspoins Flashcards

1
Q

Contraindications

A

Enterococci
Listeria
Some resistance to Klebsiella and E. Coli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Name the 1st gen. Cephalosporins.

A

Cephalexin
Cefadroxil
Cefazolin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

1st gen. Specificity

A

Gram+
(Staph, strep, pneumonia, P. Mirabillis)

Gram-
(E. Coli, Klebsiella pneumo, P. Mirabillis)

Some anaerobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

1st gen. indcations

A

GAS strep in PNC allergic
SSTI
UTI

Cephalexin
(AOM, prostatitis, bone infections)

Cefazolin
(Pre-open prophylaxis, endocarditis in PNC allergic, Septicemia)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

1st gen. contraindications

A

Anaphylactic rxn to PNC or cephalosporins

Does not cover enterococcus
Orals don’t cover H. Flu

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Cephalosporins AE’s

A 
N/V/D
DI hepatitis
Pancytopenia
Candidiasis
C-diff.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Cephalosporins PK

A

Eliminated in urine (dose for renal insufficiency)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

2nd gen. Cephalosporins

A

Cefuroxime (oral)

Cefotetan (IV)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

2nd gen. Specificity

A

Extended gram - coverage

E. Coli and Klebsiella that don’t produce betalactamase.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Cefuroxime indications

A

Gonorrhea
Early Lime disease
UTI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Cefotetan Indications

A 
UTI
SSTI
Gyn (no Chlamydia)
Peritonitis
Bone/joint
Pre-op prophylaxis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

2nd gen. contraindications

A

Enterococci

Pseudomonas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

2nd gen. AE’s

A

Same as 1st gen.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

3rd gen.

A

Cefdnir (Oral)
Cefixime (oral)

Ceftazidime (IV/IM)
Ceftriaxone (IV/IM)
Cefotaxime (IV/IM)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

3rd gen. Specificity

A

Better gram- coverage than 2nd gen.

Some cross the BBB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

2nd gen. Indications

A

Pseudomonas
Ceftriaxone with 2nd AB’s is FIRST LINE FOR GONORHHEA
Avibactam (not staph)

17
Q

3rd gen. contraindications

A

Staph (ceftazidime)

18
Q

3rd gen. Other

A

Cefdnir is the most important

Ceftazidime-avibactam indicated for complicated UTI

19
Q

3rd gen. PK

A

IM can be very painful and can be mixed with lidocaine.

Eliminated via urine (dose for renal insufficiency)

20
Q

4th gen.

A

Cefepime (IV)

21
Q

4th gen. Specificity

A 
Broad spectrum
Penetrates CSF
Pseudomonas
Strep
Enterobacter
22
Q

4th gen. Indications

A 
Meningitis
Peritonitis
SSTI
UTI
Febrile neutropenia
Pneumonia
23
Q

4th gen. AE’s

A

Same as the rest

24
Q

4th gen. PK

A

Renal elimination (renal dosing)

25
Q

5th.gen.

A

Ceftaroline (IV)

26
Q

5th gen. Specificity

A

MRSA

Nisseria

27
Q

5th gen. Indications

A

MRSA
CAP
SSTI

28
Q

5th gen contraindications

A

Ane robes

29
Q

Cephalosporins (MOA)

A

Inhibit bacterial cell wall synthesis via binding PNC-binding proteins.

Pharmacology Elon (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions