Central Pathways Flashcards
Describe the Lemniscal auditory pathway
- ICC/MGB to layer IV of primary auditory cortex
- Sensory
- Tonotopic, temporal structure encoded
Describe the non-Lemniscal auditory pathway
ICC/MGB to layer I of associative cortex
Integrative, polysensory
Broad tuning, not tonotopic, rapid habituation
Name the 2 developmental gradients in the CANS
Peripheral to Central
Cortical maturation by layers: layer I, then IV-V, later II-III
Precocious
Hearing mature at birth
Altricious
Born deaf
When is myelin density adult-like?
6-12 months of age
Neurons are 50-60% of adult size at what age?
Birth
What age are neurons adult-like
1 year of age
When is myelin density adult-like?
6-12 months of age
When is the temporal lobe formed by?
27th fetal wk
Does the complexity of neurons increase with age?
Yes
Name an intrinsic factor that affects neural connections
Gene expression
Name an extrinsic factor that affects neural connections
Sound exposure
How does deafness affect the End Bulbs of Held?
Decreased branching
How does deafness affect :
the spiral ganglion cells?
Ipsi CN?
Contra preference in auditory cortex?
SGCs: Decreased #
Ipsi CN: Decreased volume
Contra pref: Decreased preference