CENTRAL NERVOUS SYSTEM DRUGS Flashcards
What is Neuropharmacology?
It is a study of drugs that alter processes controlled by the nervous system
Neuropharmacology is divided into two and these are:
Autonomic Nervous System and Central Nervous System
What are the 2 neuron regulator?
- Axonal conduction
- Synaptic tansmission
What are the 5 steps of synaptic transmission?
- Synthesis of Neurotransmitter
- Storage of Neurotransmitter
- Release of Neurotransmitter
- Action at the receptor
- Termination of the transition
CNS drugs are used to treat what kind of disorder?
Psychiatric disorder
CNS contains 21 compounds. Give at least 3.
- Dopamine
- Aspartate
- Adenosine
What happens if you use CNS drugs for a long period of time?
- It will increased therapeutic effects
- Decreased side effects
- Tolerance and Physical dependence
What are the 2 drugs that works on ADHD and Narcolepsy?
Methylphenidate and Modafinil
It is a disorder in which the CNS neurons exhibit excessive excitability.
EPILEPSY
What are the 2 types of seizure?
- Partial Seizures
- Generalized Seizures
Why is it necessary to move the patient into a side-lying position when they are experiencing a seizure?
So that the secretion flows on the side and prevents choking.
If the seizure lasts 2–5 minutes or longer what does it called?
STATUS EPILEPTICUS
It is a type of drug that can be administered in all types of seizures.
Valproic Acid (Depakote)
Why is it prohibited to administer phenytoin and D5 water at the same time?
It will crystalized
What are the signs and symptoms of Phenytoin toxicity?
- Nystagmus
- Sedation
- Ataxia
- Diplopia
- Cognitive impairment
A type of drug used to treat partial seizures and generalized tonic-clonic seizures. It can also be used as a “sleeping pill”.
PHENOBARBITAL
A type of drug that has fewer side effects than phenytoin and phenobarbital.
CARBAMAZEPINE
Why is it prohibited to drink grapefruit juice when taking carbamazepine?
It can increase the level of absorption of this drug that can cause toxicity.
Why is Diazepam not recommended for long-term use?
It has a high potential for addiction.
It is defined as involuntary contraction of the muscle
MUSCLE SPASM
