Central Nervous System Drugs Flashcards

1
Q

What is Neuropharmacology?

A

It is the branch ofpharmacologythat deals with the action of drugs on the nervous system.

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2
Q

CNS drugs are used for?

A

It is used for psychiatric disorders, suppression of seizures, relief of pains, and production of anesthesia.

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3
Q

What is the purpose of the blood brain barrier?

A

The purpose of the blood–brain barrier isto protect against circulating toxins or pathogens that could cause brain infections, while at the same time allowing vital nutrients to reach the brain.

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4
Q

What is amphetamine?

A

It is a strong central nervous system stimulant that is used in the treatment of attention deficit hyperactivity disorder, narcolepsy, and obesity.

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5
Q

What are dopaminergic drugs?

A

These drugs directly or indirectly cause activation of dopamine receptors.

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6
Q

What are anticholinergic agents?

A

These are drugs that block receptors for ACh.

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7
Q

What is the mechanism of anti-epileptic drugs?

A

• Suppression of sodium
• Suppression of calcium influx
• Antagonism of glutamate
• Potentiation of GABA

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8
Q

What do Hydantoins treat and how does it work?

A

It is mainly used to treatseizures. Hydantoins reduce seizures by targeting the sodium channel present throughout the nerves.

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9
Q

What do barbiturates do?

A

These are depressant drugs that slow down the central nervous system (CNS), and they are commonly used to treat issues like anxiety, headaches, insomnia, and seizures. Some can also be used as an effective anesthesia.

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10
Q

What drugs are Iminostilbenes?

A

Iminostilbene isa chemical precursor of carbamazepinewhich is used primarily in the treatment of epilepsy and neuropathic pain.

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11
Q

What do benzodiazepine drugs do?

A

Benzodiazepines are a type of sedative medication. This means theyslow down the body and brain’s functions. They can be used to help with anxiety and insomnia.

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12
Q

What is the mechanism of action of carboxylic acid derivatives?

A

It suppresses neuronal firing through blocking sodium channels and calcium influx, and augment inhibitory influence of GABA.

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13
Q

What is a Gabapentin?

A

Itis ananticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures.

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14
Q

What is the mechanism of action of centrally acting agents?

A

Centrally acting drugs area type of medicine that can be used to treat high blood pressure. Also known as central alpha antagonists, they work directly on the part of the brain that controls blood pressure.

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15
Q

What is the indication of Dantrolene sodium?

A

It is indicated for use in chronic disorders characterized by skeletalmuscle spasticity, such as spinal cord injury, stroke, cerebral palsy and multiple sclerosis.

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16
Q

Neuromuscular blocking drug is intended to?

A

• Relax skeletal muscles during surgery
• Reduce the intensity of muscle spasms on drug-induced seizures.
• Manage patients who are fighting the use of ventilator to help with breathing

17
Q

What is a non-depolarizing blocking drug?

A

It compete for receptor sites withacetylcholinein the neuromuscular junction, with the magnitude of block dependent on the availability of acetylcholine, the concentration of neuromuscular blocker in the neuromuscular junction, and the affinity of the agent for the receptor.

18
Q

What is depolarizing blocking drugs?

A

It effects thecholinergic receptorsof theneuromuscular junction, initially causing contractions evident asfasciculationsfollowed by an interval of profound relaxation.

19
Q

What do you mean by abstinence syndrome?

A

Abstinence syndrome occurs when clients abruptly withdraw from a substance to which they are physically dependent.

20
Q

What is an opioid addiction?

A

An opioid addiction is a powerful urge to use certain medicines called opioids.