Central nervous system Flashcards
cerebral peducles
join both hemispheres to the midbrain
lobes of the brain and boundaries
frontal- anterior to central sulcus and above lateral sulcus
temporal - below lateral sulcus
parietal - behind central sulcus and above lateral sulcus
occipital- behind the parieto-occipital sulcus
Parts of the Lateral Sulcus (AKA sylvian fissure)
posterior ramus - the part that extends posteriorly above the temporal lobe
Ascending ramus - penetrate the inferior frontal gyrus at anterior end of the fissure. Posterior to anterior rami
— separating the pars triangularis from the pars opercularis of the frontal operculum.
anterior rami - penetrate the inferior frontal gyrus at the anterior end of the fissure
— separating the pars orbitalis form the pars triangularis of the frontal operculum.
The transverse temporal gyri, also called Heschl’s gyri- primary auditory cortex
parts of the inferior frontal gyrus
- divided by the anterior and ascending rami
- pars orbitalis, pars triagularis and pars opercularis
- region of motor speech area (Broca’s) on the left
Frontal Opercula
- frontal operculum begins at the anterior ramus of the lateral fissure and extends to the inferior portions of the precentral gyrus, and temporal lobe, encompassing the pars triangularis and opercularis of the inferior frontal gyrus
- covers the insula
Insula cortex structure
- various long and short gyri
- completely surrounded by a circular sulcus
precentral gyrus and post central
- anterior to central fissure (Fissure of Rolando)
- precentral is primary motor cortex
post central is posterior and is primary somatosensory cortex
Structure of the frontal lobe
- precentral gyrus running in coronal plane
- running out from this are 2 sulcus that divide it into the superior, middle and inferior frontal gyrus
structure of temporal lobe
superior and inferior temporal sulcus separate the lobe into the superior, middle and inferior temporal gyrus
parietal lobe structure
superior and inferior parietal lobules separated by transverse sulcus
the lateral sulcus and superior temporal sulcus project into the inferior lobule
the end of the lateral sulcus is enclosed by the supramarginal gyrus
the end of the superior temporal gyrus is enclosed by the angular gyrus
occipital lobe structure
occipital lobe is divided by an imagianry line from parietal and temporal lobes. This line extends from the parieto-occipital sulcus on a roughly 45 degree angle to the preoccipital notch (formed by an indentation by dura folding over the transverse sinus)
a line from the occipital notch to the lateral fissure indicates the join of the parietal and temporal lobes
Cingulate gyrus and sulcus
Cingulate gyrus is located above the corpus callosum
cingulate sulcus is superior to the cingulate gyrus
Medial brain anatomy
cingulate gyrus and sulcus - see others
medial frontal gyrus lies above the cingulate sulcus - extends anteriorly
where the central sulcus curves medially - is enclosed by the paracentral lobule
parieto-occipital sulcus separates the
—— cuneus - part of the occipital lobe located posteriorly to this
precueneus - located anterior to the parieto-occiptal sulcus and behind the paracentral lobule
the calcarine sulcus is inferior to the cuneus and runs anteriorly from the occipital pole
lingual gyrus - lies below the posterior part of the calcarine sulcus
– limited by the collateral sulcus
— the collateral sulcus divides the lingual gyrus and parahippocampal gyrus from the fusiform gyrus
calcarine sulcus
forms a y shape with the parieto-occipital sulcus on the medial part of the brain
- posterior part fo caclarine sulcus divdies the cuneus and lingual gyrus
- other arm of teh y is the
- stem of the Y is the anterior calcarine sulcus which forms the calcar avis in the posterior cornu of the lateral ventricle.
inferior frontal brain surface
- gyrus rectus - a straight gyrus directly next to midline of frontal lobe
- — olfactory bulb lies on this
- orbital gyrus - lateral to olfactory bulb - these leave prominent marks on the frontal bone
inferior occipital and temporal
concave and oblique in deformity to lie against the tentorium cerebelli
occipitotemporal sulcus (lateral) lies lateral to the collateral sulcus (medial)- both run the inferior surface on the temporal lobe
medial to collateral is the parahippocampal gyrus - which curves anteriorly to form the uncus
—- posteriorly appears continuous with the lingual gyrus
midline structures viewed inferiorly
structures are inferior to floor and 3rd ventricle between temporal poles and anterior to cerebral peduncles
- optic tracts diverge from the chiasma - under the cover of the temporal poles
- posterior to chiasma - tuber cinereum - pituitary stalk projects
- behind the tuber cinereum - the mamillary bodies project
- behind the mamillary bodies - deep in the angle of the cerebral peducles- the posterior perforated substance
- lateral to the chiasma- the anterior perforated substance
- around the anterior perforated substance the olfactory tract can be seen diverging
basal ganglia
consist of the caudate nucleus, lentiform nucleus (outer part - the putamen and inner part- globus pallidus), amygdaloid body and claustrum
- amygdaloid body often excluded
- substantia nigra and subthalamic nucleus often included - as connect extensively with the lentiform nucleus
important notes:
1) corpus striatum formed by caudate and lentiform nucleus due to interconnections
2) lentiform nucleus is main efferent pathway of the corpus striatum
3) exert supraspinal control of muscle movements - control range, rate and co-ordination
structure
- inputs from cortex, thalamus and substantia nigra to the corpus striatum
- outputs- globus pallidus - outputs to the thalamus, subthalamic nucleus, substantia nigra and reticualr formation
- – fibres to thalamus- ansa lenticualris and ansa fascicualris, pass ventral and dorsal to to subthalamic nucleus
- — the fascicularis passes through fibres of the internal capsule along with the subthalamic fascicularis– connecting the globus pallidus and subthalamic nucleus
caudate nucleus
comma shaped
has a head, body and tail
body curves around the lateral part of thalamus to form the tail which projects toward the amygdala body
caudate wraps around the internal capsule
whole length of its convexity projects into the lateral ventricle
lentiform nucleus
biconvex shape, buried in the hemisphere
lateral is putamen, medial is globus pallidus
putamen is joined to the head of the caudate by myelinated and unmyelinated fibres which pass through the anterior capsule - give its straited appearance
amygdaloid body and claustrum
attached to the tail of the caudate
sits in the roof of the inferior horn of the lateral ventricle
the claustrum is a thin saucer shaped, lies lateral to the putamen
white matter types in the cortex
commissural - - join to hemispheres
— corpus callosum, but also anterior, posterior and habenular commissure
Association (arcuate) - connect parts within the cortex
projection - join grey matter of the hemisphere with subcortical nuclei in the hemisphere and brain stem and spinal cord nuclei
Internal capsule
corona radiated - fibres fanning out from the internal capsule to join the grey
- composed 5 parts: anterior limb, genu and posterior limb, sublentiform and retrolentiform parts
- anterior limb lies between head of the caudate medially and lentiform nucleus laterally
- — contains frontopontine fibres which arborise in the pontine nucleus
- — also has fibres from frontal eye field - which run to occulomotor nucleus for accomodation-convergence reflex
- genu- bend at the apex of the globus pallidus
- — corticonuclear fibres are here - from cortex to brain stem motor nuclei
- posterior limb - between thalamus medially and lentiform nucleus laterally
- – anterior 2/3rds are corticospinal fibres (behind the corticonuclear of the genu)- pass down and decussate to for lateral corticospinal tract –> arborize at anterior horn cell
- — head fibres lie anteriorly, followed by arm, hand, trunk, leg perineum
- — in brain stem same order but medial to lateral
note: genu and 2/3rd of posterior = motor control for entrire body
posterior limb, retrolentiform and sublentiform internal capsule
- ant 2/3 - corticospinal fibres
- beside and behind the corticospinal are the thalamocortical fibres (sensory from opposite side)
- retrolentiform: posterior part of lentiform nucleus parieto, occipito and temporopontine fibres
- — these occupy the lateral 1/3 of the base of the cerebral peduncle
- — important: contains optic radiation -> fibres from cell bodies of the lateral geniculate nucleus to visual cortex
- Sublentiform: a further part of these fibres rin from the medial geniculate body below the posterior end of the lentiform nucleus - to the superior temporal gyrus - forming the auditory radiation
corpus callosum
- starts at anterior commissure at the upper end of the lamina terminalis
- 4 parts: rostrum, genu, body, splenium
- splenium is a free border
- forceps minor- arc of fibres that radiate to frontal lobe off the rostrum
- forceps major - fibres that spread from the splenium to the occipital lobe
- forms room of anterior horn and body of ventricle
- tapetum - the fibres of teh corpus callosum that forms the lateral wall of the inferior and posterior horns of the ventrcile
cortical areas: MsI, MsII, motor speech area, posterior speech area,
MsI - precentral gyrus- motor for body. Face lies lowest, followed by hand, arm, trunk and leg and perineum on medial part. Inputs: cerebellum and thalamus, outputs corticonuclear and cortico spinal MsII- receives from basal nuclei- postural mechanisms Motor speech (brocas, areas 44, 45)- inferior frontal gyrus on left. located on pars triangularis (motor aphasia - difficulty finding right words) posterior speech area (Wernicke's)- in the posterior parts of the superior and middle temporal gyrus and into the lower part of parietal lobe (involved in understanding speech)
frontal eye field, SMI and SmII and gustatory area
fontal eye field (6,8, 9) - voluntary eye movement and accommodation reflex- centre of middle frontal gyrus
SmI- touch, kinaesthesia aand vibration (ordered the same as MsI)
SmII- pain localisation (registration of pain occurs at thalamic level)
gustatory area- inferior part of post central gyrus in the frontoparietal operculum- near tongue taste area of SmI
auditory area, olfactory area
auditory (41 and 42)- hidden in the lateral sulcus in the anterior transverse temporal gyrus. It also extends into the superior temporal gyrus below the sulcus- this part is surrounded by the auditory assocaition cortex
— cochlear is represented bilateral
—receive fibres from Medial geniculate body via auditory radiation
olfactory- uncus of the parahippocampal gyrus
Visual areas
area 17 - medial surface of occipital lobe, in calcarine sulcus- more specifically it lies in the lower lip of the anterior part of the sulcus and along both upper and lower lips of the posterior part and extends approx 1cm onto the lateral surface of the occipital lobe as far as the lunate sulcus
—- the true visual area is characterised by a white line, (stria of Gennari) - which bisects the cortex
areas 18 and 19- surrounding cortex of the stria of Gennari
- each cortex registers the opposite visual field
— upper half of cortex recieves fibres from upper half of retina and lower half from the lwoer (ie the lower visual field is carried by the upper fibres- so the visual fields are crossed)
– macula is at the posterior part of the cortex and peripheral parts as moving anteriorly
visual pathway (to LGN)
retinal rods and cones–> bipolar cell–> ganglion cells (inner retina netx to vitrous body, 1 cell for 1 cone and 1 cell for 80 rods, 2nd order neurons) –> ganglion cell axons runs through optic disc and form optic nerve –> nasal fibres decussate at optic chiasma–> optic tract (left responsible for right vision and vice versa)–>optic tract passes around the cerebral peducle high up against the temporal lobe reaching the side of the thalamus –> divides into two (superior brachium, the smaller branch, passes between the Lateral and medial geniculate bodies to superior colliculus; the larger branch continues on to the LGN)
optic nerves is covered in meninges- which attaches to the sclera - anterior to optic foramen - has dura, arachnoid and pia mater – > posterior to foramen has just pia mater to the optic chiasma
the optic chiasma is attached to the floor of the 3rd ventricle
visual pathway (LGN and beyond)
the lateral geniculate nucleus lies below the pulvinar on posterior thalamic surface
– has 6 layers - fibres from the retina on same side (temporal retina) synapse ar layers 2, 3, 5; nasal fibres (ones that have crossed) at 1, 4 and 6
From LGN –> optic to occipital cortex
— optic radiation lies in calcarine sulcus
superior brachium–> superior colliculus–> tectobulbar and tectospinal tracts –> general light reflexes (blinking, turning away from bright light)
—- superior colliculi are linked by the posterior commissure - general light reflexes are bilateral
Pupillary light reflex
pupillary light reflexes fibres do not synapse at the superior colliculus - but rather the pretectal nucleus located at the upper lateral margin of the superior colliculus in teh tegmentum
- the pretectal nucleus - passes to the Edinger Westpthal nucleus on both sides –> sphincter pupillae
- crossing from the pretectal nucleus and also the nasal fibres ensures bilateral pretectal nculeus are excited to light–> direct (same side contract) and consensual (opposite contracts)
- — lesion of the pretectal nucleus - Argyll Rovbertson - small, does not constrict to light, but restricts to accommodation-convergence (as this is a different pathway not involving the pretectal nucleus)
visual field defects
1) complete optic nerve –> blindness in that eye
2) optic chaism- bitemporal hemianopia
3) left optic tract - homonymous hemianopia- left sided causes right sided vision loss (medial on same side and lateral on opposite)
4) lower fibres of optic radiation - temporal lobe - on left causes right upper quadrantic homonymous hemianopia
5) lower optic radiation - left causes right lower quadantric homonymous hemianopia
6) anterior left visual cortex- caused by PCA stroke - causes a right homonymous hemianopia with macula sparing because macula is spared as it is posterior and supplied by the MCA
7) posterior visual cortex- on left gives right homonymous macular defect - often traumatic
limbic system
1) teh septal and piriform areas of the cerebral cortex near lamina terminalis (anterior boundary of 3rd ventricle)
2) uncus, insula and cingulate and parahippocampal gyri
3) amygdaloid body
4) hippocampus, fibria, fonix and mamillary body
fornix
- efferent pathway of the
choroid plexus
formed by blood vessels lined by pia mater and ependymal cells
- secretes CSF
oculomotor nucleus innervations and locations
motor somatic: superior, medial, inferior rectus, inferior oblique and levator palpebrae superioris
visceral motor: Edinger Wespthal - to ciliargy ganglion for sphincter pupillae and cillairy body
location is near mdilin in floor of aqueduct of midbrain level with superior colliculus
CSF flow
lateral ventricle –> interventricular foramen (foramen of Monro)–> 3rd ventricle–> cerebral aqueduct–> 4th ventricle –> central canal of spinal cord–> filum terminale
– only apertures in roof of 4th ventricle –> opens into subarachnoid space
lateral ventricle boundaries
white matter forms walls elsewhere, except in places where the the bottom of sulcus grey matter form wall- these include the parahippocampal, calcarine, and colateral sulcus (form convexities in the ventricle) and the thalamus and caudate nucleus
choroid fissure
C shaped ………….. (to do)
anterior horn boundaries (triangle shape)
medial wall - septum pellucidum
roof- fibres that run laterally from the genu and rostrum of the corpus callosum (forceps minor)
lateral wall - is the caudate nucleus - meeting the roof at a lateral angle
– the caudate is separated from the fornix at the floor by the septum pellucidum - which atatches the fornix to the corpus callosum
behind the anterior column of the fornix and anterior to anterior pole of thalamus at floor of anterior horn is the interventricular foramen
— the choroid travels through here without going into the anterior horn
body of the ventricle boundaries
lies behind the level of the interventricular foramen
floor- thalamus and body of caudate
—– the thalamostriate groove lies between the the thalamus and caudate
——— within this groove lies: stria medullaris - a band of white matter running the length of the caudate; thalamostriate vein
roof: copus callosum
medial wall: crus and body of fornix and septum pellucidum
between the thalamus of the floor and the fornix of the medial wall - the choroid plexus evaginates with pia and ependyma– forming the start of the choroid plexus. The choroid plexus is limited anteriorly by the interventicular foramen
posterior horn boundaries
floor: collateral eminence (convex in shape) - which is formed by the collateral sulcus
medial wall: consists of two convexities - the upper is the bulb of the posterior horn- formed by fibres of forceps major; the lower is the calcar avis formed by the calcarine sulcus
roof and lateral wall: tapetum of the corpus callosum, with the optic radiation lying against the tapetum in the lateral wall