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pharmacology > Central Nervous System > Flashcards

Central Nervous System Flashcards

1
Q

Conducting an action potential down the axon of the neuron

a. Synaptic Transmission
b. Axonal Conduction
c. both a and b

A

b. Axonal Conduction

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2
Q

Process by which information is carried across the gap between neuron and postsynaptic cell

a. Synaptic Transmission
b. Axonal Conduction
c. both a and b

A

a. Synaptic Transmission

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3
Q

How many compounds do CNS contains that serve as neurotransmitter?

a. 21
b. 23
c. 30

A

a. 21

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4
Q

Decreased response occurring in the course of prolonged drug use

a. Tolerance
b. Physical dependence
c. both a and b

A

a. Tolerance

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5
Q

State in which abrupt discontinuation of drug use will precipitate a withdrawal syndrome

a. Tolerance
b. Physical dependence
c. both a and b

A

b. Physical dependence

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6
Q

It is most commonly prescribed anticonvulsant drug

a. Phenobarbital
b. Carbamazepine
c. Phenytoin

A

c. Phenytoin

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7
Q

Effective against partial seizures and generalized tonic-clonic seizures but not absence seizures. Can be used as daytime sedative “sleeping pills”

a. Phenobarbital
b. Carbamazepine
c. Phenytoin

A

a. Phenobarbital

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8
Q

Active against partial seizures and tonic-clonic seizures but not absence of seizures

a. Phenobarbital
b. Carbamazepine
c. Phenytoin

A

b. Carbamazepine

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9
Q

It is restricted to acute treatment of status epilepticus, not recommended for long-term use due to high potential for addiction

a. Diazepam
b. Clonazepam
c. IV Lorazepam

A

a. Diazepam

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10
Q

DOC for acute management of status epilepticus

a. Diazepam
b. Clonazepam
c. IV Lorazepam

A

c. IV Lorazepam

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11
Q

A treatment for absence seizures

a. Diazepam
b. Clonazepam
c. IV Lorazepam

A

b. Clonazepam

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12
Q

What is the therapeutic level for Phenytoin?

a. 50-100 mg/ml
b. 10-20 mcg/ml
c. 4- 12 mcg/ml

A

b. 10-20 mcg/ml

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13
Q

What is the therapeutic level for Carbamazepine?

a. 50-100 mg/ml
b. 10-20 mcg/ml
c. 4- 12 mcg/ml

A

c. 4-12 mcg/ml

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14
Q

What is the therapeutic level for Carboxylic acid?

a. 50-100 mg/ml
b. 10-20 mcg/ml
c. 4- 12 mcg/ml

A

a. 50-100 mg/ml

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15
Q

An abstinence maintenance that decreases unpleasant effects resulting from abstinence (anxiety/restlessness)

a. Buprenorphine (subutex)
b. Acamprosate
c. Naltrexone
d. Clonidine (catapres)

A

b. Acamprosate

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16
Q

An abstinence maintenance, opioid antagonist that suppresses craving and pleasurable effects of alcohol

a. Buprenorphine (subutex)
b. Acamprosate
c. Naltrexone
d. Clonidine (catapres)

A

c. Naltrexone

17
Q

Opioid withdrawal support, Aids in withdrawal effects related to autonomic hyperactivity (diarrhea, nausea, vomiting)

a. Buprenorphine (subutex)
b. Acamprosate
c. Naltrexone
d. Clonidine (catapres)

A

d. Clonidine (catapres)

18
Q

Opioid withdrawal support, Used for detoxification and maintenance, decreases craving, administered SL, MI, IV

a. Buprenorphine (subutex)
b. Acamprosate
c. Naltrexone
d. Clonidine (catapres)

A

a. Buprenorphine (subutex)

19
Q

Bind to a carrier protein and act at a receptor resulting in increased GABA in the brain

a. Baclofen
b. Gabapentin
c. Dantrolene sodium

A

b. Gabapentin

20
Q

Most effective for spasticity of cerebral origin and used for treatment malignant hyperthermia

a. Baclofen
b. Gabapentin
c. Dantrolene sodium

A

c. Dantrolene sodium

pharmacology (3 decks)

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