Cellule Flashcards

1
Q

Exemples de cellules bi-nucléées

A

Cardiomyocytes, hépatocytes

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2
Q

Comment appelle-t-on importine et exportine?

A

Karyopherines

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3
Q

Que fait HMT?

A

Methylation histones qui bloque transcription

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4
Q

Quand sont actifs APC et SCF?

A

APC : M, G1
SCF : Fin G1, S, G2

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5
Q

Caractéristiques de la prophase

A
  • Formation du fuseau mitotique
  • Centrosomes se séparent
  • Chromosomes condensés
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6
Q

Caracteristiques de la prometaphase

A
  • Rupture membrane nucléaire
  • Cellule s’arrondit
  • Chromosomes s’attachent aux microtubules
    + FIN PROCESSUS INTERPHASE
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7
Q

Quelle histone spéciale se trouve dans kinetochores?

A

CENP-A au lieu de H3

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8
Q

Combien de paires de kinetochores?

A

46

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9
Q

Consequence d’une endomitose VS endocycle

A

Endomitose : cellule polynuclees
Endocycle : polyploïdes (ex. Foie)

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10
Q

De quoi une mitochondrie a besoin pour laisser s’échapper cytochrome C?

A

Bac ou Bak activé

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11
Q

De quoi ont besoin cellules pour initier apoptose?

A

Signaux de cellules voisines

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12
Q

Processus de chaîne respiratoire

A

Nutriments -> Acétylène-CoA -> Cycles de Krebs/acide citrique -> NADH et succinate -> donneurs é -> gradient protons -> ATP synthase

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13
Q

Que se passe-t-il si inhibe fission mitochondries?

A

Cycle cellulaire s’arrête en G2/M et induit apoptose

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14
Q

Mécanisme de la thermogenèse (découplage)

A

Norepinephrine (Froid) -> acides gras libres -> UCP1 -> tissu adipeux brun (chaleur)

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