Cellular Physiology

Question 1

Cellular physiology:

Body water content 42 L

**5.5L
Plasma volume 3L
Extracellular fluid volume 17L
Intracellular fluid volume 25L
Interstitial fluid volume 13L
Hematocrit ** men: 40-52% women: 37-48%
Hemoglobin concentration ** men: 160-170g/l women: 135-145g/l
Blood plasma Na+concentration 135-147mM
Blood plasma H+ concentration 40nM
Blood plasma K+ concentration 3.5-5.0mM
Blood plasma Ca2+ concentration and its fractions Total: 2.1-2.8mM Free: 1.1-1.4mM
Blood plasma Cl- concentration 95-105mM
Blood plasma HCO3- concentration 22-28mM
Blood plasma protein concentration 60-80g/L
Intracellular Na+ concentration 10-15 mM
Extracellular Na+ concentration 135-147mM
Intracellular H+ concentration pH=7.2
Intracellular K+ concentration 120-150mM
Cytosolic(ICF) Ca2+ concentration 100nM
Intracellular Cl- concentration 20-30mM
Intracellular HCO3- concentration 12-16 mM
Blood plasma osmolarity and oncotic pressure 290osm/ 25uμgmm(πc)
Resting membrane potential of skeletal muscle cells **-95mv
Resting membrane potential of neurons ***-70mv
Conduction velocity of different type of nerves
Myelin sheath : 1) Aα : 80-120m/sec
2) Aβ : 35-75m/sec
3) Aδ : 5-30m/sec
Unmyelinated sheath : 0.3-1m/sec
Equilibrium potential of Na+ in neurons: 60mV
Equilibrium potential of K+ in neurons: -90mV
Equilibrium potential of Ca2+ in neurons: 130mV
Equilibrium potential of Cl- in neurons: -70mV

Answer 1

42 L

Question 2

Blood volume

Answer 2

5.5 L

Question 3

Plasma volume

Answer 3

3 L

Question 4

Extracellular fluid volume

Answer 4

17 L

Question 5

Intracellular fluid volume

Answer 5

25 L

Question 6

Interstitial fluid volume

Answer 6

13 L

Question 7

Hematocrit

Answer 7

men 40-52% women 37-48%

Question 8

Hemoglobin concentration

Answer 8

men: 160-170g/l women: 135-145g/l

Question 9

Blood plasma Na+concentration

Answer 9

135-147mM

Question 10

Blood plasma H+ concentration

Answer 10

40nM

Question 11

Blood plasma K+ concentration

Answer 11

3.5-5.0 mM

Question 12

Blood plasma Ca2+ concentration and its fractions Total:

Answer 12

2.1-2.8mM Free: 1.1-1.4mM

Question 13

Blood plasma Cl- concentration

Answer 13

95-105mM

Question 14

Blood plasma HCO3- concentration

Answer 14

22-28mM

Question 15

Blood plasma protein concentration

Answer 15

60-80g/L

Question 16

Intracellular Na+ concentration

Answer 16

10-15 mM

Question 17

Extracellular Na+ concentration

Answer 17

135-147mM

Question 18

Intracellular H+ concentration

Answer 18

pH=7.2

Question 19

Intracellular K+ concentration

Answer 19

120-150mM

Question 20

Cytosolic(ICF) Ca2+ concentration

Answer 20

100nM

Question 21

Intracellular Cl- concentration

Answer 21

20-30mM

Question 22

Intracellular HCO3- concentration

Answer 22

12-16 mM

Question 23

Blood plasma osmolarity and oncotic pressure

Answer 23

290osm/ 25uμgmm(πc)

Question 24

Resting membrane potential of skeletal muscle cells

Answer 24

-95mv

Question 25

Resting membrane potential of neurons

Answer 25

-70mv

Question 26

Conduction velocity of different type of nerves

Myelin sheath

Answer 26

: 1) Aα : 80-120m/sec

                      2) Aβ : 35-75m/sec
                      3) Aδ : 5-30m/sec

Question 27

Unmyelinated sheath

Answer 27

0.3-1m/sec

Question 28

Equilibrium potential of Na+ in neurons:

Answer 28

60mV

Question 29

Equilibrium potential of K+ in neurons:

Answer 29

-90mV

Question 30

Equilibrium potential of Ca2+ in neurons

Answer 30

130mV

Question 31

Equilibrium potential of Cl- in neurons

Answer 31

-70mV