Cellular Organelles Flashcards

1
Q

Golgi Apparatus

A
Modification of carbohydrates
attached to glycoproteins and
proteoglycans
 Polysaccharide &
oligosaccharide synthesis
 Synthesis of sphingomyelin
and glycosphingolipids
 Sorting secretory products
 Marking lysosomal enzymes
with mannose-6-phosphate
(M6P)
 Packaging & storing secretory
products into secretory
granules or vesicles
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2
Q

Mitochondria

A

outer and inner membrane and matrix

- Makes ATP, signaling, cell differentiation and cell death

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3
Q

Lysosomes

A

contain digestive enzymes that degrade

organelles and biomolecules

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4
Q

Peroxisomes

A
•synthesis and degradation of
hydrogen peroxide
 ß -oxidation of long-chain fatty acids
 bile acid and cholesterol synthesis
 detoxify alcohol
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5
Q

Smooth ER

A
 Glycogen metabolism
 Lipid synthesis
 Phospholipid synthesis
(other membranes)
 Detoxification
 Steroidogenesis
 Calcium regulation
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6
Q

Rough ER

A
Proteins are modified &
assembled
 Segregation of proteins
for intracellular use and
 Export from the cell
(collagen, cell membrane
proteins)
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7
Q

Clathrin-coated vesicles

A
  • can be involved w/ both endocytosis and exocytosis
    Golgi –> lysosomes
    exterior of cell -> lysosomes (eg. cholesterol)
    Dynamin - aids in pinching off
    Adaptins - aids clathrin binding to the vesicle membrane
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8
Q

COP-coated vesicles

A

(coat protein), transporting
products between stacks of the Golgi apparatus (COPIcoated
vesicles), and from the endoplasmic reticulum
to the Golgi apparatus (COPII-coated vesicles)

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9
Q

Primary lysosomes

A

the storage site of lysosomal hydrolases
 No digestive events
 Homogeneous
 Inactive enzymes

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10
Q

Secondary lysosomes

A

catalytic process
 Digestive enzymes
 Heterogeneous
 Active enzymes

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