Cells of the CNS

Question 1

Describe the astrocytes.

Answer 1

• Most abundant of the glial cells
• Communicate with each other (gap junctions and chemical signals) and with neurons
• Structural support - scaffolding during devlopment
• Maintenance of neurotransmitters
• Modulate synpase function

Question 2

Describe the microglia.

Answer 2

• Immune cells of the CNS
• Act as macrophages - release cytokines
• Resting or activated
• Resting - homeostatic role
• Activated - motile and pro-inflammatory
• Role in neurodegenerative disease

Question 3

Describe the oligodendrocytes.

Answer 3

• Form the myelin sheath around neuronal axons

Question 4

Describe the ependymal cells.

Answer 4

• Epithelial cells - line the ventricles
• Secrete CSF
• Form blood brain barrier