Cells In Brain Flashcards
Typical neurone
Several main parts: soma, axon and dendrites
Inside of neurone separated from outside by neuronal membrane
Two main types of cell in ns
Neurones- sense changes in environment, convey info to other parts of rain
Glia - insulates supports and nourishes neurones
Soma (cell body)
Watery fluid inside cell is cytosol
Cytoplasm is everything in cell membrane except from nucleus
Nucleus inside nuclear envelope. Containss DNA
Mitochondria, golgi apparatus, smooth ER
Cytoskeleton
Scaffolding of neurone
Gives it the shape
Microtubules, microfilaments and neurofilaments
The axon
Begins at axon hillock
No rough ER and few ribosomes
Protein comp is different than soma
Middle of axon is axon proper. End is axon terminal
How can neurones be classified
By total no of dendrites, axons, axon length, connections and tpe of neurotransmitter they use
Classification: no of axons
Unipolar (one axon, soma is a projection) sensory from skin
Bipolar (2 axons, soma lies in the middle) olfactory, retina
Multipolar (most in the brain are multipolar)
Classification: dendrites
Shape: stellate cells (star shaped), pyramid cells, double bouqet, basket cells
Presence of spines: spiny or aspinous
All pyramid cells are spinous. Stellate can be either
Classification: axon length
Golgi type 1- projections that extend from one part of brain to other
Golgi type 2- dont extend beyond vicinity of cell body. Local circuitry
Classification: connections
Primary sensory
Motor
Interneurones
Glia
Support neuronal functions Astrocytes Myelinating glia Ependymal cells Microglia
Astrocytes
Most numerous glia
Fill space between neurones. Decides whether neurone grows or retracts
Regulates chemical content of extracellular space. K+
Envelopes synapse preventing spread of neurotransmitter
Membrane has NT receptors that can trigger electrical events in astrocyte
Myelinating glia
Oligodendrocytes (CNS) and schwann cells (PNS)
Provides layers of membrane that insulate axons (myelin)
Sheath interrupted at nodes of ranvier
One oligodendrocyte myelinates many axons, one schwann cell only myelinates one axon
Ependymal cells
Lining of fluid filled ventricles
Play role in directing cell migration during brain development
Microglia
Function as phagocytes to remove debris from dead or degenerating neurones and glia