Cells and the Immune System Flashcards

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1
Q

What is immunology [1]

A

The study of the immune system

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2
Q

Name ways that the body prevents pathogens from entering? [3]

A
  • Skin
  • Enzyme in the tears
  • HCl stomach acids
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3
Q

What is the non-specific response? [1]

A

Does not distinguish between pathogens and is instant

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4
Q

What is the specific immune response? [1]

A

Is the response to a particular pathogen which provides much longer lasting immunity

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5
Q

Explain how the skin is a physical barrier for pathogens? [2]

A

Constantly flaking so prevents pathogenic bacteria from colonising

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6
Q

What are phagocytes? [1]

A

White blood cells that travel in the blood which can engulf pathogens

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7
Q

What is the process by which phagocytes engulf pathogens called? [1]

A

Phagocytosis

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8
Q

Histamine produced at the site of an infection cause the blood vessels cause the blood vessels to dilate, why? [2]

A

Increase lumen therefore increase blood flow

So more WBCs can get to the area of infection

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9
Q

What is a toxin? [1]

A

A chemical released by a pathogen that can damage cells

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10
Q

Name the 4 types of pathogen [4]

A
  • Bacteria
  • Virus
  • Fungus
  • Protoctista
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11
Q

What are the two types of specific immune response? [1]

A

Cell Mediated and Humoral

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12
Q

What is an antigen? [1]

A

A foreign molecule usually a protein which can cause an immune response

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13
Q

What are the two types of lymphocyte? [2]

A

T cells

B cells

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14
Q

Describe the activation of a T-Cell? [3]

A
  • Helper T cells receptors specific to the antigen (either presented on a macrophage or just in the blood)
  • Helper T cell becomes active when they join
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15
Q

What does a T cell do once activated? [4]

A
  • Alert cytotoxic T cells to area
  • Release cytokines which stimulate the B cells specific to this antigen to clone and become plasma cells
  • Stimulate macrophages to engulf pathogens by phagocytosis
  • Develop into memory cells
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16
Q

What three things can activate a T cell? [3]

A
  • Cancer cell displaying foreign antigens
  • Macrophage
  • Cell with a virus host
17
Q

Where are B cells made? [1]

A

In the bone marrow

18
Q

Why are B cells specific? [1]

A

Because each B cell has a unique receptor

19
Q

Describe the activation of a B cell? [3]

A

1) Activated by the cytokines of an activated T-helper cell
2) Can engulf antigens through phagocytosis, they then display this antigen on the surface and wait for activation by a T-helper cell

20
Q

Once activated what do B cells produce? [2]

A
  • Memory B cells

- Plasma cells which can secrete antibodies

21
Q

Describe the structure of an antibody [2]

A

Y shaped with a hinge region with two antigen binding sits at the end of each chain

22
Q

What are antibodies made from? [1]

A

Proteins

23
Q

What is a monoclonal antibody? [1]

A

An antibody grown from one single B cell