Cells And The Immune System Flashcards
Antigens
Molecules (usually proteins) that can generate an immune response when detected by the body
Where antigens found
On surface of cells
Antigens used for
Used by immune system to identify pathogens, abnormal body cells, toxins, and cells from other individuals of the same species
4 main stages of immune response
- Phagocytes engulf pathogens
- Phagocytes activate T-cells
- T-cells activate B-cells, which divide into plasma cells
- Plasma cells make more antibodies to a specific antigen
Phagocytes
White blood cell that carries phagocytosis
Found in boood and tissues
Phagocytosis
Engulfment of payjoges
Phagocytosis steps
- Phagocytes recognises the foreign antigens on a pathogen
- The cytoplasm of the phagocytes moves round the pathogen, engulfing it
- The pathogen is now contained in a phagocytise vacuole, in the cytoplasm of the phagocyte
- A lysosome fuses with phagocytise vacuole - the lysozymes break down the pathogen
5, phagocyte then presents the pathogens antigens - sticks antigens on its surface to activate other immune system cells
1st stage of immune response
Phagocytosis
2nd stage of immune response
Phagocytes activate T-cells
T cells have receptor proteins on its surface that bind to complementary antigens presented to it by phagocytes
Activates the T-cell
Diff T cells respond in diff ways
T-cells
White blood cell
Has receptor proteins on its surface that bind to complementary antigens presented to it by antigens
How do Helper T-cells respond to being activated
Release chemical signals that activate and stimulate phagocytes
Cytoxic T-cells
Kill abnormal and foreign cells
B-cells
Secrete antibodies