Cells and Stuff from potpourri Flashcards
Histamines
Vasodilator, itching. Released by mast cells
Prostaglandins
Pain, Vasodilation, Chemotaxis. Released by mast cells
Leukotrienes
Vasodilation, chemotaxis.
Bradykinin
Released by kinin system; Vasodilation, vascular permeability, pain.
Cytokines
Signaling molecules, cell communication. Primarily produced by: Macrophages, T-helper cells.
Leukocytes
White blood cells. Work with fighting infection. Granulocytes and Mononuclear
Neutrophils
Early responder, phagocytosis, release toxins
Eosinophils
Allergic and parasitic reactions; regulate inflammatory response
Basophils
Mast cells! pro-inflammatory chemicals, allergic reactions, acute and chronic inflammation, wound healing
Monocytes
Macrophages! longer living, phagocyotsis, secrete cytokines, present antigens to activate T cells, clean up
Lymphocytes
Adaptive immunity. B-Cells - produce antibodies; T-cells - T-4 helpers, T-8 killes
Systemic manifestations of inflammation
Fever; Leukocytosis - increase; Lab changes: RBC sedimentation rate, C-reactive protein increase