Cells Flashcards
Osmotic pressure
Minimum amount of pressure required to stop the diffusion of pure water across the membrane. If a vessel is divided into two Chambers and pure water is placed into one chamber while a solution such as sugar water is placed in the other chamber the water level will rise on the side of the greater solute concentration therefore the diffusion of water will continue in this direction until the pressure becomes too great The water will have moved from high to low water concentrations.
Passive transport
The movement of substances across the cell membrane without the input of energy.
Entropy
Unavailable energy disorder
Nonpolar molecules
Hydrophobic electrons are shared equally and there is no resulting charge
Polar molecules
Have either a positive or negative charge
Examples of nonpolar molecules
Oxygen gas carbon dioxide an uncharged lipids are not repelled by the hydrophobic interior of the membrane
What are forms of passive transport
Simple diffusion osmosis and facilated diffusion
Osmosis
The passive transport of water across the membrane most polar molecule cannot use simple diffusion but water molecules are small enough to slowly squeezed between the phospholipids
What can water use to channel proteins to increase the rate of osmosis
Aguaporins
When proteins are used to transport substances down their concentration gradients
Facilitated diffusion
Gradient
Increase or decrease
Facilitated diffusion
Molecules diffuse across the plasma membrane with assistance from membrane proteins such as channels and carriers a concentration gradient exists for these molecules so they have the potential to diffuse into or out of the cell by moving down it.
Large polar and or charged substances require shielding from the interior of the membrane and they may use
Channel or Carrier proteins to assist in their transport
Osmosis does not require what to be driven by the difference in solute
ATP
Active transport
Energy is used to move solutes into or out of the cell
During what transport are substances pumped against their concentration gradients from areas of low to high concentration
Active transport
Active transport is required for processes such as
The maintenance of a membrane potential and the uptake of glucose by intestinal cells even between meals
The pumping of solutes by a carrier protein is directly coupled to the hydrolysis of ATP
Primary me active transport
Relies on ATP to generate an electrochemical gradient and it is this grattent that directly drives the active transport of a different solute
Secondary active transport
As one solute moves down as graduate another is
Pumped up its gradient
When both solutes move in the same direction it is called
Symport
When solutes move in opposite direction it is called
Antiport
Endocytosis and exocytosis are types of
Active transport that employ vesicles to import or export substances. they do not necessarily move solutes up their concentration gradient
Endocytosis
Is cellular process in which substances are brought into the cell
The process of bringing substances out of the cell
Exocytosis
Example of passive transport
Riding a bicycle down a hill where you don’t need to put an energy
Diffusion and osmosis have in common
Both move from a high to low concentration
Osmosis is simply
The diffusion of water
Active transport requires
Energy
Example of active transport
Riding a bike up the hill
What are the three types of active transport
Pump or channel, endocytosis, and exocytosis
A cell uses a what to move objects from low concentration to high concentration
Pump or channel
Membrane channels act as
Doorways that lets particles move passively
Diffusion can move
Materials into or out of the cell from high to low concentrations
Concentration gradient
Tells us which particles are going to move passively
All channels move substances down their concentration gradient by
Diffusion and does not require energy
Unlike carrier proteins channels interact very weakly with the
Solutes they transport for allowing us to move rapidly across the membrane
Channel proteins that allow the passage of water are called
Aquaporins and they’re always open
Ion channels are usually gated and they open and close
In response to various stimuli
What channels respond to changes in membrane potential and are vital to generating electrical impulses and nerve in cardiac cells
Voltage-gated
Ion channels open in response to The binding of a levante such as a hormone or neurotransmitter
Ligand gated
Ion channels respond to a physical stimulus such as a stretching of the membrane and are useful and sensory
Mechanically gated
Types of vesicular transport that are used for transport a very large particles or bulk quantities of smaller particles AR examples of active transport due to requiring energy
Exocytosis and endocytosis
During exocytosis products and waste are transported via
Vesicle to the cell membrane where the vesicle fuses releasing its contents into the extracellular environment
Exocytosis components
Glycoproteins and glycolipids
What involves the injection of fluid large particles are Target molecules and the process entails the cell membrane folding inward pinching off into a vesicle
Endocytosis
Pinocytosis
The ingestion of fluids
Pinocytosis
Takes in any enzymes and nutrients that happened to be available during endocytosis
Phagocytosis
Taking in of particles eating them sometimes even entire cells. immune system cells ingest harmful bacteria before destroying them.
Receptor-mediated endocytosis
A form of endocytosis that targets certain molecules such as low density lipoproteins that are low in concentration outside the cell
Both rough and smooth endoplasmic reticulum contain
Cisternae
Cisternae
Is the continuous membranes of the rough and smooth endoplasmic reticulum
Is continuous with the nuclear envelope and it’s ribosomes studded cisternae have the appearance of flattened sacs
Rough ER
The ribosome synthesizes polypeptides which are guided into the lumen before being modified packaged in a vesicle and sent to different regions within the cell often the Golgi apparatus
Rough ER
Ribosomes are sent out of the ER via
Exocytosis
The cisternae is more tubular and shape and lack ribosomes
Smooth ER
Is involved in synthesize of lipids such as phospholipids and cholesterol
Smooth ER
The part of liver cells that detoxifies drugs and regulates and stores calcium ions
Smooth ER
Secretary proteins
Proteins destined to be exported from the cell
Secretary proteins and proteins that are associated with plasma membrane are synthesized on ribosomes that are bound to the cytoplasmic side
Of the rough endoplasmic reticulum and these ribosomes are not permanently fixed
Translocons
Ribosomes that are not permanently fixed and will bind to sites
Ribosomes that are free in the cytosol will produce proteins that will remain
Only in the cytosol of the cell
As a polypeptide chain is growing out of a bound ribosome during translation the chain is fed
Through a tiny pour into the lumen of the rough ER
Enzymes in the lumen May modify proteins by
Convey Lily bonding a carbohydrate to form a glycoprotein.
The endoplasmic reticulum constitutes roughly
Half of the plasma membrane in a cell
The membrane system of the rough ER is connected to the
Outer nuclear membrane
Forming flattened sacs that connect to each other in a manner that resembles a multi-story parking garage in the endoplasmic reticulum
Cisternae
Helicoidal sheets of the membrane structure of the endoplasmic reticulum
Terasaki ramps
Newly synthesized proteins are packaged in the transport vesicles in the endoplasmic reticulum and are coated with
Protein complexes that help direct each vesicle to its destination
Mitochondria
Powerhouses of the cell that produce the most of the cells ATP
Mitochondria has how many membranes
2 which include the outer membrane that acts as a selective barrier and the inner membrane where most of the ATP is made
What does the inner membrane of the mitochondria do
The inner membrane is folded into structures called cristae and is within these folds that the electron transport chain of aerobic respiration.
What is between the membranes of the mitochondria
The intermembrane space where a proton motive force is used to drive chemiosmosis which is the making of ATP
Chemiosmosis
Synthesizing ATP
What is inside of the matrix of the mitochondria
Ribosomes and mitochondria DNA
How many genes does DNA of the mitochondria carry in humans
37 genes
Mitochondria plays a role in program cell death called
Apoptosis
Mitochondria
Makes energy
Mitochondria
Organelle found in Eukaryotic cells.
Mitochondria makes
ATP
Mitochondria ATP stands for
Adenosine triphosphate
Mitochondria oxidizes
Glucose and fatty acids
Plants make their own glucose via
Photosynthesis
Plants also have
Mitochondria
Plants use glucose to convert
Energy
Structure of mitochondria
Inner membrane which helps with the transport chain houses to compartments including intermembrane space and matrix base. the outer membrane contains proteins called porins that lets sugars and ions pass
Mitochondria DNA
Mtdna
Mitochondria functions
Cellular respiratory cellular differentiation, cellular degeneration
Mitochondria converts glucose into
Pyruvate and then into ATP
Mitochondria ATP turns into
Acetyl COA
Stages of mitochondria
Electron transport chain and oxidative phosphate
Proteins in mitochondria that causes apophysis
Bcl-2 and cytc-c
Mitochondria is described as semi-autonomous because
Each one has its own genome and ribosomes and produces many of its own protein
Mitochondria copies that are circular DNA molecules before
Undergoing fission
Mitochondria does not rely on nuclear genes to produce many of the proteins required for DNA replication instead it
Gets its proteins imported from the cytosol
Endosymbiont theory
Suggests that mitochondria were once free-living prokaryotes
Nucleus
Small structure that contains the chromosomes and regulates the DNA of a cell
Nucleus
Regulates the DNA of a cell
Nucleus
Designing structure of eukaryotic cells
All eukaryotic cells have
A nucleus
A nucleus is responsible for
Passing on genetic traits between generations
Nucleus contains 6 parts
The nuclear envelope, nucleoplasm, a nucleolus, nuclear pores, chromatin and ribosomes
Chromosomes
Highly condensed thread-like rods DNA
DNA
Shorts for the deoxyribonucleic acid is a genetic material that stores information about the plant or animal
Chromatin
Consists of the DNA and protein that makes up chromosomes
Nucleolus
Structure contained within a nucleus consists of protein and a small round does not have a membrane, is involved in protein synthesis and synthesizes and stores RNA ribonucleic acid
Nucleolus
Involved in protein synthesis and stores RNA
Nuclear envelope
This encloses the structure of the nucleus and it consists of inner and outer membranes made of lipids
Nuclear pores
These are involved in the exchange of material between the nucleus and the cytoplasm
Nucleoplasm
This is the liquid within the nucleus it is similar to the cytoplasm
Not only is DNA found in the nucleus but also
In mitochondria and chloroplast
The nuclear envelope contains double membranes with pores made out of large protein complexes that regulate the passage of
RNA, ribosomal subunits, proteins, ions and signal molecules
Enclosed in the double membrane the nucleus is
Nucleoplasm, chromatin, and a non membrane-bound nucleus which produces ribosomal subunits
Chromatin
DNA and associated histone proteins
The inner nuclear membrane is covered by a mesh of protein filaments called
The nuclear lamina which stabilizes the nuclear us while regulating events such as DNA replication and cell division
The outer membrane of the nucleus is continuous with the
Endoplasmic reticulum
The nucleus is responsible for
Storage of DNA, the site of DNA replication, and transcription the synthesis of RNA.
The largest structure inside the nucleus that is responsible for producing ribosomes subunits
Nucleolus
Has no membrane and is made of three regions in the nucleus.
Fibrillar center FC - is where the ribosomal RNA genes are located and transcribed.
Dense Fibrillar Center DFC - processes the pre rrna
Granular -GC -immature ribosomal subunits are assembled
All are RNA is synthesized in the nucleolus except
5s-rrna which is made in the nucleoplasm before being incorporated into ribosomal subunits.
The nucleolus disappears early in mitosis of what stage
Prophase
What stage does the nucleolus reappear in mitosis
The final stage telophase
When the nucleolus first appears early in mitosis it appears
10 small units at various chromosome sites called nucleolus organizer regions in NORS
Is the double membrane that encloses the nucleus separating the nucleoplasm from the cytoplasm of the cell
Nuclear envelope
There is a 2240 nanometer gap between the two phospholipid bilayers
Nuclear envelope
Two phospholipid bilayers called regarding the nuclear envelope
Perinuclear space
The pores in the nuclear envelope each are made of hundreds of proteins called
Nucleoporins and is an Octagonal Aqueous channel
The proteins in the nuclear envelope interact with transporter proteins called
Karyopherinswhich shuttle large molecules like RNA and certain proteins back and forth between the nucleus and the cytoplasm
Smaller molecules and ions are able to diffuse through the pore complex of the nuclear envelope without
The aid of a transporter
The cores of the nuclear envelope are essential for the import of the
Enzymes in nucleotides that are required for DNA synthesis and transcription and export of mRNA, TRNA and ribosomal subunits that are required for translation
The outer membrane of the nuclear envelope is continuous with the
Endoplasmic reticulum and the lumen of the ER is open to the Perinuclear space which allows for the easy exchange of materials between two organelles.
The nucleoplasm mix side of the inner membrane is lined with a network of protein filaments called
Nuclear lamina and he supports the nuclear us while eating in the organization of chromatin
Lumen
Inner space
The stage of the cell cycle in which the nucleus divides
Mitosis
Longest stage in mitosis that prepares for division by copying organelles and duplicating chromosomes
Interphase