Cell Ultrastructure Flashcards
Define limit of resolution.
The minimum distance that two objects can be distinguished at.
Why are electron microscopes capable of finer resolution than light microscopes?
Limit of resolution is proportional to wavelength
An electron beam has a much shorter wavelength than a beam of visible light
Describe the structure of the cell membrane (phospholipid bilayer).
Made up of amphipathic phospholipid molecules
Forms an impermeable barrier to water soluble molecules
Contain integral and peripheral proteins and cholesterol embedded in the bilayer
Describe the functions of the plasma membrane.
Selectively permeable Transports materials along the cell surface Endocytosis Exocytosis Intercellular adhesion Intercellular recognition Signal transduction
Describe the structure and function of the glycocalyx.
Cell coat comprising of oligo and polysaccharide side chains outside of the plasmalemma
Acts as a way of giving the cell specificity
Describe the function of the nucleus.
Stores the cells dna
Coordinates the cells activities, metabolism, growth, protein synthesis and mitosis.
Describe the structure and function of heterochromatin.
Heterochromatin is condensed chromatin in a solenoid state
It is not being expressed
Describe the structure and function of euchromatin.
Chromatin that is not condensed, beads on a string state
Being expressed
Describe the function of the nucleolus.
Site of transcription of rRNA
Site of ribosome synthesis
Describe the structure and function of the nuclear envelope.
Double layered membrane with many holes called nuclear pores
Studded with ribosomes and occasionally continuous with RER
Separates nucleus from cell cytoplasm
Pores regulate what passes between nucleus and cytoplasm
Describe the structure and function of the smooth endoplasmic reticulum.
Flat sheets of membranes and tubules without ribosome receptors
Synthesis of cholesterol and lipids
Detoxification of certain drugs and toxins
Regulate muscles contraction and relaxation due to specialisation to release ca in muscles only.
Describe the structure and function of the rough endoplasmic reticulum.
Flat sheets of membranes continuous with nuclear envelope
Contains ribosomal receptors
Synthesis, modification and packaging of proteins
Describe the structure and function of ribosomes.
Contains 2 subunits composed of proteins and rRNA
Surface and catalyst for protein synthesis
Describe the structure of the Golgi apparatus.
Clusters of vesicles, tubules and flattened membrane bound cisternae
Convex entry cis face close to nucleus
Concave entry trans face oriented towards cell membrane
Describe the function of secretory vesicles.
Condense and release contents at cell surface by exocytosis