Cell types and locations Flashcards
Chief Cells
Live 60- 90 days
Produce: Pepsinogen & gastric lipase
Found: Gastric region
Goblet Cells
Found: Fewest in duodenum Most found in ileum
Paneth Cells
Live ~20 days
Found: Crypts (intestinal glands)
Function: Produce Lysozyme
Surface Mucus cells
Live- 3-5 days
Produce- Thick, visible mucus that traps bicarb
secrete- Bicarbonate ions (buffering)
Found in isthmus of the gastric region - Thick visible mucus
Neck Mucus
Live- 6 days
Produce a soluble, less alkaline mucus (slightly acidic)
Function- To lubricate gastric contents
Parietal (oxyntic) cells
Live- 150 to 200
secretes - HCl .8 pH buffered immediately to 1-2 pH.
Function- necessary for vitamin B12 absorption
low # of Parietal cells
Can lead to low amounts of Intrinsic factor ( necessary for RBC maturation)
Hepatocytes
Microvilliated cuboidal cells possessing lateral bile canaliculi between adjacent hapatocytes
Produce- Bile
Kupffer cells
Also know as Stellate macrophages- resident macrophages; develop from monocytes
Fuction: phagocytosis of debris & aged RBC’s ; act as an APC
Ito Cells
Hepatic Stellate Cells-
Functions: store lipids for immediate use; store Vitamin A;
Produces- collagen I,III,IV, and growth factors
pit cells
Natural killer cells?
Enterocytes
surface absorptive cells- contain microvilli
Main Functions: Absorb water and nutrients & terminal digestion in glycocalyx cells produce the enzymes and absorb the monosaccharides and peptides created.
clear cells
Cholangiocytes- have many microvilli
function: concentrate bile by absorbing water
Found in the Luminal wall Mucosa
DNES cells
Live 60-90 days
= Enteroendcrine cells
located in the stomach
Type D: produces somatostatin, inhibits release of hormones by nearby DNES cells & HCL release
Type EC: produces serotonin and substance P, increases gut motility
Type G: produces gastrin. stimulates HCL & pepsinogen secretion, gastric motility, and regenerative cells in body of stomach.
