Cell Signaling Flashcards
G proteins are bound to guanosine diphosphate (GDP) when they’re inactive, and when a ligand binds.
guanosine triphosphate (GTP)
are seven-pass transmembrane receptors. The associate with G-proteins made of alpha, beta, and gamma sub units.
G-protein coupled receptors
Gs protein stimulates the enzyme .
adenylate cyclase
Phospholipase C cleaves phosphatidylinositol 4,5-bisphosphate into .
inositol trisphosphate and diacylglycerol
Gi protein inhibits the enzyme .
adenylate cyclase
Activated adenylate cyclase takes adenosine triphosphate or ATP, and transforms it into .
cyclic adenosine monophosphate (cAMP)
Gq protein activates the enzyme .
phospholipase C
Signal is the process where a receptor protein changes in response to binding a ligand and activates the second messenger proteins.
signal transduction