Cell membrane structure Flashcards

1
Q

What are plasma membranes made of?

A
  • A double layer of phospholipids- bilayer
  • Contains proteins, cholesterol, glycoproteins, and glycolipids
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2
Q

What is the structure of a phospholipid?

A
  • 1 phosphate group- hydrophilic
  • 1 glycerol
  • 2 fatty acids- hydrophobic
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3
Q

How do phospholipids arrange themselves in water?

A
  • Hydrophilic heads face outwards towards water
  • Hydrophobic tails face inwards away from water
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4
Q

What is diffusion?

A
  • Net movement of particles from high to low concentration
  • Moves down a concentration gradient
  • Passive process
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5
Q

What molecules can diffuse directly through the bilayer?

A
  • Non-polar
  • Uncharged molecules
  • Small polar molecules
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6
Q

What molecules cannot diffuse through the bilayer?

A
  • Large polar molecules and ions
  • They are rejected by the hydrophobic fatty acid tails
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7
Q

How do charged ions pass through the membrane?

A
  • Through ion channel proteins
  • Bind to a specific binding site
  • Move down their concentration gradient- facilitated diffusion
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8
Q

What is facilitated diffusion?

A
  • Passive process
  • Moves molecules down a concentration gradient
  • Uses channel proteins or carrier proteins
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9
Q

How do carrier proteins work in facilitated diffusion?

A
  • Molecule binds to carrier protein
  • Carrier protein changes shape
  • Molecule is released on the other side
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10
Q

What are intrinsic proteins?

A
  • Span the entire bilayer
  • Hydrophobic R groups face outwards
  • Hydrophilic R groups face inwards- allow diffusion of molecules
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11
Q

What are the functions of membrane proteins?

A
  • Glycoproteins: Cell recognition, communication, tissue formation
  • Extrinsic proteins: Act as receptors for hormones or messengers
  • Channel proteins: Facilitate diffusion of charged ions
  • Carrier proteins: Transport molecules across the membrane
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12
Q

What is the function of cholesterol in the membrane?

A
  • Sits between phospholipid tails
  • Maintains stability and fluidity of the membrane
  • Prevents the membrane from becoming too rigid or too fluid
  • Prevents crystallization at cold temperatures
  • Holds fatty acid tails together at warm temperatures
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13
Q

What increases membrane fluidity at low temperatures?

A
  • Double bonds between carbon atoms in fatty acid chains
  • Shorter fatty acid chains
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14
Q

What is the fluid mosaic model?

A
  • Fluid: Phospholipids and proteins move within the bilayer
  • Mosaic: Scattered proteins form a pattern
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15
Q

Why is it called the fluid mosaic model?

A
  • Phospholipids move within the membrane
  • Contains different types of proteins (e.g., glycoproteins, carriers, channels)
  • Based on experimental evidence
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