Cell Membrane Structure Flashcards

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1
Q

What is the structure of a phospholipid?

A

A phospholipid has a hydrophilic head and a hydrophobic tail.

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2
Q

Since phospholipids have hydrophilic and hydrophobic parts, what are they called?

A

Amphipathic

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3
Q

Are phospholipid tails saturated or unsaturated?

A

They can be both.

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4
Q

What type of phospholipid tails are straight?

A

Saturated phospholipid tails.

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5
Q

What type of phospholipid tails are bent?

A

Unsaturated phospholipid tails.

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6
Q

Why are unsaturated phospholipid tails bent?

A

The presence of a double bond.

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7
Q

Does the straightness of phospholipid tails change based on fluid content?

A

Yes, the more fluid there is, the more bent they are.

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8
Q

What is the primary molecule of the cell membrane?

A

Phospholipids.

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9
Q

How are phospholipids synthesized?

A

Through the endoplasmic reticulum.

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10
Q

How are phospholipids transported?

A

They are transported as vesicles to the cell membrane.

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11
Q

Who proposed the idea of a phospholipid bilayer?

A

Gorter and Grendel in 1925.

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12
Q

What does the fluidity of the cell membrane allow for?

A

It allows for materials to move through the cell membrane via endo and exocytosis.

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13
Q

Who discovered membranes are made of lipids?

A

Overton (1899)

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14
Q

Who discovered membranes are a lipid bilayer made of phospholipids that have a hydrophilic head and a hydrophobic tail?

A

Gorter and Grendel (1925)

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15
Q

Who discovered the membrane includes globular protein molecules attached to each side of the lipid bilayer?

A

Davson and Danielli (1935)

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16
Q

Who discovered the membrane is a fluid bilayer of lipids with embedded proteins?

A

Singer and Nicolson (1972)

17
Q

What model of the cell membrane do we use today?

A

The mosaic model.

18
Q

What are integral proteins?

A

Proteins that span the entire membrane and are permanently attached.

19
Q

What are peripheral proteins?

A

Proteins that are not attached permanently and that attach to the surface, or sometimes integral proteins.

20
Q

What molecule moderates the fluidity of the cell membrane in eukaryotes?

A

Cholesterol, by making the membrane more fluid at lower temperatures and vice versa.

21
Q

What is the structure of cholesterol?

A

Hydroxyl, hydrocarbon rings, and a hydrocarbon tail.

22
Q

Is cholesterol amphipathic?

A

Yes, it has both hydrophilic and hydrophobic parts.

23
Q

Where is cholesterol in the cell membrane model?

A

It is between the phospholipids, with the head of cholesterol near the head of the phospholipid and the tail of the cholesterol between the phospholipid tails.