Cell injury Flashcards

1
Q

Give the four types of hypoxia and how they might be caused

A

Hypoxaemic hypoxia low partial pressure of oxygen at altitude or reduced absorption secondary to lung disease

Anaemic hypoxia decreased ability of haemoglobin to transport oxygen from anaemia or carbon monoxide poisoning

Ischaemic hypoxia interruption fo blood supply - blockage of a vessel for heart failure

Histiocytic hypoxia - inability to utilise oxygen in cells deu to disabled oxidative phosphorylation enzymes
- cyanide poisoning

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2
Q

Give a few examples of toxins that can cause cell injury and death

A
glucose and slat in hypertonic solutions 
high conc of oxygen 
poisons 
pollutants 
insectides, pesticides 
medicines 
alcohol
narcotic drugs 
asbestos
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3
Q

Give to immune mechanisms that can cause cell injury and death

A

hypersensitivity reaction - over vigorous immune reaction

autoimmune reactions

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