Cell injury

Question 1

Necrotic cells show increased eosinophilia due to

Answer 1

loss of cytoplasmic RNA, denaturation of cytoplasmic proteins

Question 2

Necrotic cells have more glassy homogeneous appearance since

Answer 2

loss of glycogen particles

Question 3

what are myelin figures seen in necroses

Answer 3

Intracellular whorled phospholipid masses

Question 4

Differentiate between Karyolysis, pyknosis and karyorrhexis

Answer 4

Karyolysis- enzymatic degradation of DNA, Basophilia of chromatin fades
Pyknosis - nuclear shrinkage and increased basophilia
Karyrrhexis- Pyknotic nucleus undergoes fragmentation.

Question 5

Architecture of deed tissues is preserved in which type of necrosis

Answer 5

Coagulating Necrosis

ps: ischaemia due to obstruction in vessel- coagulative necrosis of all organs except brain

Question 6

example of liquefactive necrosis is

Answer 6

hypoxic death in CNS , focal bacterial or fungal infections