Cell Divisions, Diversities and Differentiation Flashcards
A *slight* deeper insight into what cells really do in their lives!
What is mitosis?
- Type of nuclear division that produces 2 genetically identical daughter cells to each other and parent
What is Chomatin?
- This is the complex of nucleic acids and histone protiens, being DNA unravelled state!
What are Chomosomes?
- the condensed structure of the DNA double helix!
What are Chromatids?
- These are structures of copied chromosomes during the preparation of cell division
- The “divided and duplicated” form of the chomosomes….
What are Centromeres?
AND LOOK HERE RN!!!!!
- This is the center of chromosomes where the spindle fibres will attach during metaphase!
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!!!!NUMBER OF CENTROMERES = NUMBER OF CHROMOSOMES!!!!
What are sister chromatids?
These are the 2 copies of the cell’s original chromosomes!
How can there be an increase in number of chromatids, but same number of chromosomes
AHEM!!!!!!!!!!!
- Thes is due to the centromere-counting rule, where we count chromosomes in this manner!
ALWAYS THE CASE, SO NEVER FORGET!
What are homologous chromosomes?
- These are the MATCHING PAIRS OF CHROMOSOMES, each from the correspondonding parent cell! (sperm+egg)
What is the acronym for remembering the Cell Cycle Stages????
I-PMAT-C!!!!!
gotta know them in order………..!
What takes place during Interphase?
- DNA Replication
- Cell growth in size
- Organelle duplication
How can we split up the massive Interphase stage into its sub-processes???
AND EXPLAIN EACH OF ‘EM!
- The G1 Stage: main Organelle Replication and increase in Cell Size
- The S Stage: just DNA Replication!
- The G2 Stage: Stimulating protien production to allow Chromosome Condensation for mitosis stage………..
What takes place during each of the Cell Cycles’s checkpoints?
- G1 Checkpoint: Checking for DNA damages and correct cell sizes
- G2 Checkpoint: Checking for errors in DNA Replication, before moving to mitosis
- Metaphase Checkpoint: Checking forf even distribution of chromosomes during division!
What is the ledgdendary G0 Stage?
- This is where Senescent Cells (oldy cells with max division no.50) chill, with no more mitosis!
- This is also where cells are before apoptosis takes place!
cell differentiation and neurones may also forever be in this stage!
What protiens are actually involved with the cell cycle checkpoints??
- POSITIVE REGULATORS: CDK + Cycline > the protiens that INITIATE THE FOLLOWING STAGES OF CELL CYCLE!
- NEGATIVE REGULATORS: P53 Supressor Protiens > the protiens that HALT THE CELL CYCLE AND BRINGS THE G0 Stage!
What happens in each of the mitosis stages in the Cell Cycle?
remember I-PMAT-C………………
- Prophase: Chromosome Condensation, where nueclear membrane will break down
- Metaphase: Chromatids attach to the spindle fibres of centriolesvia the centromeres, where Chromosomes will line at the equator!
- Anaphase: Chromosomes are pulled away towards opposite poles via spindle fibres
- Telophase: 2 fresh new nuclear envelopes will form around dublicated chromatids