Cell division topic 1.6 Flashcards
Cell cycle
The cell cycle is an ordered set of events that culminates in cell division
Interphase
An active phase of the cell cycle where many metabolic reactions occur
* Consists of G1, S and G2 stages
M phase
The period of a cell cycle in which the cell and contents divide
* Consists of mitosis (P, M, A, T) and cytokinesis
Normal metabolism cannot occur during M phase, so key
events must occur during interphase to prepare for division:
- DNA replication (during S phase)
- Organelle duplication
- Cell growth
- Transcription / translation
- Obtaining nutrients
- Respiration (cellular)
Supercoiling
During mitosis, chromatin condenses via supercoiling to
become tightly packed chromosomes
Mitosis
Mitosis is the division of a diploid nucleus
into two genetically identical diploid nuclei
This process of cell cloning is needed for
many important processes:
- Tissue repair
- Organism growth
- Asexual reproduction
- Development of embryos
Cytokinesis
Cytokinesis is the process of cytoplasm division, whereby a cell splits in two
Cytokinesis in animals
Microtubules form a concentric ring and
contract towards the centre (centripetal)
Cytokinesis in plants
Vesicles form at the cell centre and fuse
outwards to form a cell plate (centrifugal)
Mitotic Index
The mitotic index is a measure of the proliferative
status of a cell population (i.e. number of dividing cells)
Formula for Mitotic index
Mitotic index = Cells in mitosis/Total number of cells