cell division/embryology/energy Flashcards
interphase
when cell isn’t dividing Gap 1 = cell growth S = DNA Doubles centrioles double Gap 2= cell growth and prep for division longest stage of cell cycle
checkpoints
- internal and external signals provide stop and go signals at checkpoints
- cyclins and cyclin dependant kinases control the cycle
checkpoint failure?
often causes mutations and genomic arrangements resulting in genetic instability
birth defects + cancer
cell cycle
- mitotic phase and interphase alternate
- highly regulated
- checkpoints determine fate of the cell
diploid cells
2 sets of each chromosome- 1 from each parent
haploid cells
1/2 chromosomes 23
prophase
1st phase- condensation of chromosomes, disappearance of nucleolus, chromatids condense (chromosome x’s), microtubules are made for structure
metaphase
2nd phase- chomosomes attach to microtubules. start to be pulled towards edges, chromosomes line up in a line in the middle of the cell
anaphase
chromosomes separate, egg shape, ana=back
telophase
crease forms between cells, chromosomes go back to chromatin
cleavage
fission between 2 new cells before they break, done by cytokinesis
mitosis
- decision of nucleus of 2 diploid, (2n) somatic cells
- asexual reproduction, growth, repair
binary fission
cell division of prokaryotes
- DNA doubles
- cell elongates
- cell splits in half
G (sub 0)
takes place after G1
- cells get stuck and never return to cell cycle
- cells of the central nervous system
cytokinesis
divides the cytoplasm of the daughter cells equally
in plant cells- cell plate
in animal cells- cleavage furrow
meiosis
- makes sexual reproduction possible
- Haploid (n) gametes are produced from germ cells
- nuclear division of gametes
zygote
1st cell formed after fertilization
what triggers a cell to divide?
- size
- demand
- DNA signal
- cancer/damaged DNA
what stops cell division?
- dna signal
- cell touching borders
- death
- demand changes
- gametes
hayflick limit
number of times a cell can divide before it dies
~50
telomeres get shower with each cell division, when telomeres are gone, cell dies
ends seem to unravel
why we age and die
telomere
compound structure at the end of a chromosome
homologous chromosome
- 2 of each chromosome exists in each cell, except gametes
- they are identical in the types/locations of genes
- 1 set is from dad and one from mom
- orientation during meiosis is random, ensuring a nice mix of each
fertilization
- fusion of gametes
- increases variation
- restores diploid number
meiosis I
(1st of 2 rounds)
- crossing over, mix up DNA
- chromosomes reduced to 23 duplicated chromosomes
meiosis II
turns 23 duplicated chromosomes into 23 unduplicated chromosomes
telomerase
- prevents unraveling and can lengthen telomere
- some cancer cells produce it
- HeLa cells from Henrietta Lax- good for research bc they’re immortal
stages of development
egg & sperm-> fertilization -> cleavage -> gastrulation -> organogenesis -> metamorphosis
cleavage
division of zygote into smaller cells every 12-24 hours
morula
solid ball of cells
blastula
hollow ball of cells
gastrulation
- the movement of cells to create germ layers
- starts at dorsal lip
- results in gastrula