cell division diversity and differentiation Flashcards
What is interphase?
The part of the cell cycle where the cell is not dividing
What happens in G0 phase?
This is the resting phase where cells undergo apoptosis, senescence or differentiation
what happens in G1 phase?
This is the growth phase where the organelles duplicate and the transcription of genes to make RNA occurs as well as protein synthesis of enzymes that will be needed in S phase?
What happens in S phase?
This is where the DNA duplicates - housekeeping genes are duplicated first
Why does S phase occur rapidly?
During replication the DNA base pairs are exposed which makes them susceptible to mutations so needs to occur fast to limit exposure.
What happens in G2 phase?
Chemicals ensure the cell is ready for mitosis by stimulating proteins that will be involved in forming the spindle fibres as well as this the cell grows.
What are the 3 things mitosis is needed for?
Asexual reproduction, growth and tissue repair.
What happens in prophase?
The chromatins shorten and condense and the DNA supercoils. The nuclear envelope breaks down and the spindle fibres form between centrioles.
What happens in metaphase?
The chromatids attach to the spindle fibres via their centromeres and are at the equator region.
What happens in anaphase?
The centromere splits and the motor protein pulls the sister chromatids to opposite poles where they assume a V shape.
What happens in telophase?
A new nuclear envelope forms
What happens in cytokinesis?
The cell splits into 2 each with a nucleus. In animals the plasma membrane folds inwards
What are the final products of mitosis?
2 genetically identical daughter cells which are clones of each other and the parent
What is meiosis?
used for sexual reproduction by combining 2 pieces of genetic material via fertilisation
What are the 8 stages of meiosis?
Prophase 1- chromatin condenses and DNA supercoils, nuclear envelope breaksdown and spindle forms. Chromosomes come together in homologous paris and crosing over may happen between non sister chromatids causing some allele shuffling.
Metaphase 1 - attach along the equator of the spindle fibres by their centromeres. The homologous pairs are arranged randomly facing a certain way to the pole (random assortment)
Anaphase 1 - members of each pair of homologous chromosomes are pulled apart by motor proteins. Crossed over areas separate.
Telophase 1 - 2 new nuclear envelopes form and cell divided by cytokinesis.
A short interphase occurs before that repeats.