cell cycles and divisions Flashcards

1
Q

what are the 4 main events in all organisms included in the cell cycle, although they occur differently in prokaryotes and eukaryotes

A
  • cell division signals
  • DNA replication
  • DNA segregation
  • cytokinesis
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2
Q

during what process do prokaryotes divide

A

binary fission

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3
Q

give 2 examples of external factors that are cell division signals in prokaryotes

A
  • nutrient concentration
  • environmental conditions
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4
Q

what is replicated in prokaryotes

A

circular chromosome

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5
Q

where does replication start and end (3 letter name)

A

ori - start
ter - end

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6
Q

in prokaryotes where do ori regions move to after replication is complete

A

ori regions move to opposite ends of the cell, segregating the daughter chromosomes

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7
Q

what happens in prokaryotes during cytokinesis

A
  • cell membrane pinches in, protein fibres form a ring
  • new cell wall materials are synthesised, resulting in separation of the two cells
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8
Q

what happens in eukaryotes during interphase

A
  • nucleus is visible
  • cell functions occur
  • 3 growth subphases (G1, S and G2)
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9
Q

what happens at the G1 phase in eukaryotes

A
  • chromosomes are single
  • ends at G1-to-S phase when commitment is made to DNA replication and cell division (cannot be reversed)
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10
Q

what happens in the S phase in eukaryotes

A
  • DNA replicates
  • sister chromatids remain together until mitosis
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11
Q

what happens in the G2 phase in eukaryotes

A
  • cell prepares for mitosis (e.g. synthesising the structures that move the chromatids)
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12
Q

what happens during mitosis in eukaryotes

A
  • produces 2 genetically identical nuclei (barring errors in DNA replication / mutations)
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13
Q

what type of reproduction is based on mitosis

A

asexual reproduction

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14
Q

what type of reproduction requires meiosis

A

sexual reproduction

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15
Q

describe the process and results of meiosis

A
  • 2 nuclear divisions, but DNA is replicated only once
  • reduces chromosome number from diploid to haploid, with each haploid having a complete set of chromosomes
  • gametes created
  • offspring is not genetically identical to the parents
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16
Q

through which 2 processes is genetic diversity introduced via meiosis

A

recombination - crossing over
independent assortment of alleles

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17
Q

what 2 ways can inherited disorders arise due to abnormal meiosis

A

abnormalities in chromosome number
chromosome structural rearrangements ( crossing over is uneven)

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18
Q

what happens if nondisjunction occurs during meiosis I

A

2 gametes lack that chromosome and 2 gametes with 2 copies of the chromosome

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19
Q

what happens if nondisjunction occurs during meiosis II

A

one gamete lacks that chromosome, 2 normal gametes, and one gamete with 2 copies of the chromosome

20
Q

what are the advantages of being diploid

A
  • can repair DNA damage using other chromosome copy
  • recessive mutations can be masked
  • more rapid evolution possible
  • greater diversity of immune gene alleles
21
Q

what are the advantages of being haploid

A
  • more efficient cell cycle allows faster division
  • more rapid growth
  • survival in resource poor conditions
22
Q

what were the 2 successes in Mendel’s experiments

A
  • true breeeding lines (binary, predictable traits)
  • large sample size
23
Q

how do bacteria exchange genes

A

by conjunction, via a sex pilus extending from one cell to another
genetic material passes through a cytoplasmic bridge called the conjugation tube

24
Q

how do prokaryotic cells inherit DNA

A
  • DNA passes from a donor cell to recipient cell
  • donor and recipient DNA line up and crossing over can occur, changing the recipient’s genetic makeup
25
what 3 categories do plasmid genes fall into
- unusual metabolic functions - antibiotic resistance genes - genes for making a sex pilus
26
in prokaryotes, plasmids are usually transferred during what process
during conjugation
27
why is DNA replication in eukaryotes more complicated
- more than one chromosome - starts at many origins - limited to one part of the cell cycle
28
describe interphase
- nucleus is visible - cell functions occur - 3 subphases -> growth 1, synthesis, growth 2
29
describe the G1 phases in eukaryotes
- chromosomes are single - end of G1-to-S transition when a commitment is made to DNA replication + cell division
30
describe the S phase in eukaryotes
- DNA replicates - sister chromatids remain together until mitosis
31
describe the G2 phase in eukaryotes
cell prepares for mitosis -> synthesising the structures that move chromatids
32
what happens during mitosis
production of two nuclei that are genetically identical (barring errors in replication)
33
what does sexual reproduction require
meiosis
34
describe meiosis
- offspring not identical to parents - creates gametes - 2 nuclear divisions, DNA replicated once
35
how is genetic diversity generated by meiosis
recombination - crossing over during first division - independent assortment of alleles
36
how do errors in meiosis occur
- abnormalities in chromosome number - chromosome structural rearrangements - nondisjunction
37
what does euploid mean
having the appropriate number of chromosomes
38
what does aneuploid mean
having an inappropriate number of chromosomes
39
what does monosomy mean
having a loss of 1 chromosome
40
what does trisomy mean
having an extra chromosome
41
do all chromosome rearrangements result in disease
no - some contribute to genetic variation
42
what are the advantages of being diploid
- can repair DNA damage using the other chromosome copy - recessive mutations can be masked - more rapid evolution possible - greater diversity of immune gene alleles
43
what are the advantages of being haploid
- more efficient cell cycles allow faster division - more rapid growth - survival in resource poor conditions
44
what does heterogamy mean
organisms that alternate between sexual and asexual reproduction but both forms are diploid
45