cell cycle and mitosis Flashcards
part of cell structure topic
how do prokaryotic cells divide
-binary fission
-involving the circular DNA and the plasmids (if present) replicating and then the cytoplasm splitting to create two daughter cells
-each daughter cell has one copy of the circular DNA but a variable number of plasmid copies.
-viral replication occurs inside the host cells and involves the injection of the nucleic acid into the cell.
The cell cycle
made up of what three stages
- interphase ( G1, S, G2 )
-nuclear division ( mitosis or meiosis)
-cytokenisis
Interphase
-longest stage in the cell cycle
-interphase is when organelles duplicate
-the cell grows
-then DNA replicates.
Nuclear division
-either mitosis (creating two identical diploid cells) or meiosis ( creating four genetically different haploid cells)
-mitosis creates cells with identical DNA for growth and repair.
-meiosis creates gametes.
cytokinesis
-final stage
-division of the cytoplasm to create new daughter cells
4 key stages of mitosis
-prophase
-metaphase
-anaphase
-telophase
mitosis
-involves one round of division
-results in two diploid, genetically identical daughter cells.
-mitosis for growth and repaire.g clonal expansion of B cells in the humoral response
prophase
-chromosomes condense and become visible
-nuclear envelope disintegrates
-nucleolus disappears
-in animals cells: extra info
centrioles seperate and move to opposite poles of the cell
the centrioles are responsible for creating spindle fibres which are released from the both poles to create a spindle apparatus
these will attach to the centromere and chromatids in later stages
pants have spindle apparatus but lack centrioles.
metaphase
-the chromosomes align along the equator of the cell
the spindle fibres released from the poles now attach to the centromere and chromatid
anaphase
-spindle fibres start to retract and pull the centromere and chromatids as they are bound toward opposite poles
this causes the centromere to divide into two and the individual chromatids are pulled to each opposite pole
these separated chromatids and now referred to as chromosomes.
this stage requires energy in the form of ATP which is provided by respiration in the mitochondria
telophase and cytokinesis ( end of the cell cycle )
-chromosomes are now at each pole of the cell and become longer and thinner again
-the spindle fibres disintegrates and the nucleus starts to reform
-final stage in the cell cycle
-when the cytoplasm splits in two to create the two new genetically identical cells
myosinII and actin filament ring contract to cleave cell in two.
mitotic index calculation
the total number of cells
if a percentage X100