Cell Cycle And Mitosis Flashcards
3.2.2
Define mitosis
Division of a eukaryotic cell into two genetically identical daughter cells
What is the role of mitosis
- growth of multicellular organisms
- repair of damaged tissues
- replacement of worn out cells
- asexual reproduction
Describe Prophase
- chromosomes supercoil and become visible
- nuclear membrane breaks down
- centrioles migrate to opposite poles of the cell
- spindle fibres extend from the centrioles
Describe metaphase
- spindle fibres attach to the centromere of each chromosome
- chromosomes line up on the equator of the spindle
Describe anaphase
- spindle fibres shorten
- centromeres divide
- sister chromatids are pulled apart to opposite poles
Describe telophase
- spindle fibres break down
- nuclear membrane reforms
- chromosomes begin to uncoil becoming chromatin again
What happens during G1
Growth of the cell
What happens in S phase?
- DNA replication occurs
- organelles also replicate
What happens in G2?
DNA is checked and mistakes are corrected
What is a malignant tumour?
A tumour which can spread and affect other organs, cells break off and form secondary tumours
What is a benign tumour?
A tumour/mass of cells that does not spread or affect other organs
Why are tumours damaging?
- put pressure on organs
- stop organs functioning correctly
- cause blockages
Treatments for cancer
Chemotherapy
- drugs disrupt stages of the cell cycle
- prevent DNA replication
- inhibit spindle formation