Cell cycle and cell divison Flashcards
What is chromatin?
long thread like DNA in non-dividing cell
What is a chromosome?
2 chromatids- exact copies of each due to SCR held together at centromere
What is the cell cycle?
series of events cells through as they grow and divide. INTERPHASE (G1, S1, G2), NUCLEAR DIVISION, CYTOPLASMIC DIVISION
what is mitosis?
nuclear division that’s produces TWO GENETICALLY IDENTICAL DAUGHTER NUCLEI occurs in somatic body cells. for growth and repair
state the 4 (+1) stages of mitosis
interphase, prophase, metaphase, anaphase, telophase
Mitosis: interphase
G1= cell growth, protein synthesis. S1= replication of DNA. G2= proteins for division synthesised, prepares for division.
Mitosis: prophase
chromatin-> chromosome (coil & condense), nuclear envelope & nucleolus disappear, centrioles move to opposite ends, spindle fibres form
Mitosis: metaphase
chromosomes -> equator. spindle fibres connect to chromosomes
Mitosis: anaphase
centromere divides in two. chromatids to opposite ends- daughter chromosomes
Mitosis: telophase
daughter chromosomes uncoil -> chromatin. nuclear envelope & nucleolus appear. CYTOKINISIS- (animal) 2 nuclei form, two new cells. CYTOPLASMIC DIVISION
how do you find the mitotic index?
no of cells in mitosis/ total no of cells X100
how is cancer caused by mitosis?
UNCONTROLLED MITOSIS. repeatedly dividing causes irregular mass of cells that prevent other cells/ organs functioning. changes occur in genes that control cell division
What is meiosis?
two stages of nuclear division that results in 4 GENETICALLY DIFFERENT HAPLOID GAMETES (1/2 no chromosomes) reproductive organs. chromosomes (HAPLOID) -> zygote (DIPLOID)
meiosis: interphase
same as mitosis: G1, S1, G2
What are diploid cells?
each body cell contains two each chromosome: one maternal, one paternal