Cell cycle and cell divison Flashcards

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1
Q

What is chromatin?

A

long thread like DNA in non-dividing cell

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2
Q

What is a chromosome?

A

2 chromatids- exact copies of each due to SCR held together at centromere

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3
Q

What is the cell cycle?

A

series of events cells through as they grow and divide. INTERPHASE (G1, S1, G2), NUCLEAR DIVISION, CYTOPLASMIC DIVISION

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4
Q

what is mitosis?

A

nuclear division that’s produces TWO GENETICALLY IDENTICAL DAUGHTER NUCLEI occurs in somatic body cells. for growth and repair

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5
Q

state the 4 (+1) stages of mitosis

A

interphase, prophase, metaphase, anaphase, telophase

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6
Q

Mitosis: interphase

A

G1= cell growth, protein synthesis. S1= replication of DNA. G2= proteins for division synthesised, prepares for division.

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7
Q

Mitosis: prophase

A

chromatin-> chromosome (coil & condense), nuclear envelope & nucleolus disappear, centrioles move to opposite ends, spindle fibres form

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8
Q

Mitosis: metaphase

A

chromosomes -> equator. spindle fibres connect to chromosomes

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9
Q

Mitosis: anaphase

A

centromere divides in two. chromatids to opposite ends- daughter chromosomes

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10
Q

Mitosis: telophase

A

daughter chromosomes uncoil -> chromatin. nuclear envelope & nucleolus appear. CYTOKINISIS- (animal) 2 nuclei form, two new cells. CYTOPLASMIC DIVISION

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11
Q

how do you find the mitotic index?

A

no of cells in mitosis/ total no of cells X100

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12
Q

how is cancer caused by mitosis?

A

UNCONTROLLED MITOSIS. repeatedly dividing causes irregular mass of cells that prevent other cells/ organs functioning. changes occur in genes that control cell division

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13
Q

What is meiosis?

A

two stages of nuclear division that results in 4 GENETICALLY DIFFERENT HAPLOID GAMETES (1/2 no chromosomes) reproductive organs. chromosomes (HAPLOID) -> zygote (DIPLOID)

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14
Q

meiosis: interphase

A

same as mitosis: G1, S1, G2

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15
Q

What are diploid cells?

A

each body cell contains two each chromosome: one maternal, one paternal

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16
Q

what are haploid cells?

A

gametes have half normal no of chromosomes: one chromosome from each homologous pair

17
Q

meiosis: prophase I

A

same as mitosis + crossing over (CHIASMA) between non-sister chromosomes (sections swap) = GENETIC VARIATION

18
Q

meiosis: metaphase

A

bivalents line up at equater. random assortment (LINE UP RANDOMLY) = GENETIC VARIATION

19
Q

meiosis: anaphase I

A

homologous chromosomes separate

20
Q

meiosis: telophase I

A

2 haploid cells formed- each has copy of homologous chromosomes. animals= cytokiesis

21
Q

meiosis: prophase II

A

same as mitosis but spindles form at right angles to first

22
Q

meiosis: metaphase II

A

random assortment= GENETIC VARIATION

23
Q

meiosis: anaphase II

A

chromatids pulled to opposite ends

24
Q

meiosis: telophase II

A

4 hapolid cells produced each genetically different. cytokinesis