Cell Cycle Flashcards
The cell cycle
G1-S-G2-M
The cell cycle regulates the growth and replacement of genetically identical cells throughout the lift of the organism
The cell cycle consists of interphase and mitotic (M) phase
Interphase - Involves growth and DNA synthesis including G1, a growth phase; S phase, during which DNA is replicated; G2, a further growth phase
Mitotic (M) phas - Mitotic phase involves mitosis and cytokineses
In mitosis the chromosomal material is seperated by the spindle microtubules. The is followed by cytokineses, in which the cytoplasm is separated into two daughter cells.
Mitosis
prophase, metaphase, anaphase, telophase
Prophase - DNA condenses into chromosomes each consisting of two sister chromatids. Nuclear membrane breaks down; spindle microtubules extend from the MTOC by polymerisation and attach to chromosomes via their kinectochores in the centromere region.
Metaphase - Chromosomes are aligned at the metaphase plate
Anaphase - As spindle microtubules shorten by depolymerisation, sister chromatids are seperated, and the chromosomes are pulled to opposite poles.
Telophase - The chromosomes decondense and nuclear membrane are formed around them.